Novel Approaches and Biomaterials for Bone Tissue Engineering: A Focus on Silk Fibroin
Bone tissue engineering (BTE) represents a multidisciplinary research field involving many aspects of biology, engineering, material science, clinical medicine and genetics to create biological substitutes to promote bone regeneration. The definition of the most appropriate biomaterials and structur...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/15/19/6952 |
| _version_ | 1797478281682878464 |
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| author | Federica Paladini Mauro Pollini |
| author_facet | Federica Paladini Mauro Pollini |
| author_sort | Federica Paladini |
| collection | DOAJ |
| description | Bone tissue engineering (BTE) represents a multidisciplinary research field involving many aspects of biology, engineering, material science, clinical medicine and genetics to create biological substitutes to promote bone regeneration. The definition of the most appropriate biomaterials and structures for BTE is still a challenge for researchers, aiming at simultaneously combining different features such as tissue generation properties, biocompatibility, porosity and mechanical strength. In this scenario, among the biomaterials for BTE, silk fibroin represents a valuable option for the development of functional devices because of its unique biological properties and the multiple chances of processing. This review article aims at providing the reader with a general overview of the most recent progresses in bone tissue engineering in terms of approaches and materials with a special focus on silk fibroin and the related mechanisms involved in bone regeneration, and presenting interesting results obtained by different research groups, which assessed the great potential of this protein for bone tissue engineering. |
| first_indexed | 2024-03-09T21:29:43Z |
| format | Article |
| id | doaj.art-96357b94504d43a6af3b07f7947486b8 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-09T21:29:43Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-96357b94504d43a6af3b07f7947486b82023-11-23T20:59:33ZengMDPI AGMaterials1996-19442022-10-011519695210.3390/ma15196952Novel Approaches and Biomaterials for Bone Tissue Engineering: A Focus on Silk FibroinFederica Paladini0Mauro Pollini1Department of Engineering for Innovation, University of Salento, Via Monteroni, 73100 Lecce, ItalyDepartment of Engineering for Innovation, University of Salento, Via Monteroni, 73100 Lecce, ItalyBone tissue engineering (BTE) represents a multidisciplinary research field involving many aspects of biology, engineering, material science, clinical medicine and genetics to create biological substitutes to promote bone regeneration. The definition of the most appropriate biomaterials and structures for BTE is still a challenge for researchers, aiming at simultaneously combining different features such as tissue generation properties, biocompatibility, porosity and mechanical strength. In this scenario, among the biomaterials for BTE, silk fibroin represents a valuable option for the development of functional devices because of its unique biological properties and the multiple chances of processing. This review article aims at providing the reader with a general overview of the most recent progresses in bone tissue engineering in terms of approaches and materials with a special focus on silk fibroin and the related mechanisms involved in bone regeneration, and presenting interesting results obtained by different research groups, which assessed the great potential of this protein for bone tissue engineering.https://www.mdpi.com/1996-1944/15/19/6952fibroinbiomaterialsbone tissue engineering |
| spellingShingle | Federica Paladini Mauro Pollini Novel Approaches and Biomaterials for Bone Tissue Engineering: A Focus on Silk Fibroin Materials fibroin biomaterials bone tissue engineering |
| title | Novel Approaches and Biomaterials for Bone Tissue Engineering: A Focus on Silk Fibroin |
| title_full | Novel Approaches and Biomaterials for Bone Tissue Engineering: A Focus on Silk Fibroin |
| title_fullStr | Novel Approaches and Biomaterials for Bone Tissue Engineering: A Focus on Silk Fibroin |
| title_full_unstemmed | Novel Approaches and Biomaterials for Bone Tissue Engineering: A Focus on Silk Fibroin |
| title_short | Novel Approaches and Biomaterials for Bone Tissue Engineering: A Focus on Silk Fibroin |
| title_sort | novel approaches and biomaterials for bone tissue engineering a focus on silk fibroin |
| topic | fibroin biomaterials bone tissue engineering |
| url | https://www.mdpi.com/1996-1944/15/19/6952 |
| work_keys_str_mv | AT federicapaladini novelapproachesandbiomaterialsforbonetissueengineeringafocusonsilkfibroin AT mauropollini novelapproachesandbiomaterialsforbonetissueengineeringafocusonsilkfibroin |