Morphological and functional state of the epithelial cells in submandibular salivary glands after repeated amputations of the incisor teeth in adult rats

Purpose. To evaluate a morphofunctional state of the epithelial cells of the acini and ducts of submandibular glands of mature rats after repeated incisors amputation.Materials and methods. The experiment was performed on mature (2 months) white male rats, divided into groups: intact, control group...

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Main Authors: V. V. Ivanova, I. V. Milto, I. V. Sukhodolo
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2018-03-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/1115
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author V. V. Ivanova
I. V. Milto
I. V. Sukhodolo
author_facet V. V. Ivanova
I. V. Milto
I. V. Sukhodolo
author_sort V. V. Ivanova
collection DOAJ
description Purpose. To evaluate a morphofunctional state of the epithelial cells of the acini and ducts of submandibular glands of mature rats after repeated incisors amputation.Materials and methods. The experiment was performed on mature (2 months) white male rats, divided into groups: intact, control group and a group of rats subjected to repeated incisors amputation. Applying histological, histochemical and morphometric methods, we evaluated the morphological and functional state of the epithelial cells in submandibular glands of adult rats at 2, 3, 4, 6, 8, 10 and 12 weeks after repeated amputation of the incisor teeth.Results. There is an increase of submandibular gland acini area at the 3–10 week after repeated incisors amputation. The functional activity of the submandibular glands ducts and acini cells decreases at the 2–4 week of the experiment.Conclusion. As a result of repeated incisors amputation in rat submandibular glands acini and ducts epithelial cells develop reversible structural and functional changes, which are leveled by the 12th and 6th week of the experiment, respectively.
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spelling doaj.art-9635dfef7c544887bf1d18be2b5a99b92023-03-13T09:58:23ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842018-03-01171535810.20538/1682-0363-2018-1-53-58762Morphological and functional state of the epithelial cells in submandibular salivary glands after repeated amputations of the incisor teeth in adult ratsV. V. Ivanova0I. V. Milto1I. V. Sukhodolo2Сибирский государственный медицинский университет (СибГМУ).Сибирский государственный медицинский университет (СибГМУ); Национальный исследовательский Томский политехнический университет.Сибирский государственный медицинский университет (СибГМУ).Purpose. To evaluate a morphofunctional state of the epithelial cells of the acini and ducts of submandibular glands of mature rats after repeated incisors amputation.Materials and methods. The experiment was performed on mature (2 months) white male rats, divided into groups: intact, control group and a group of rats subjected to repeated incisors amputation. Applying histological, histochemical and morphometric methods, we evaluated the morphological and functional state of the epithelial cells in submandibular glands of adult rats at 2, 3, 4, 6, 8, 10 and 12 weeks after repeated amputation of the incisor teeth.Results. There is an increase of submandibular gland acini area at the 3–10 week after repeated incisors amputation. The functional activity of the submandibular glands ducts and acini cells decreases at the 2–4 week of the experiment.Conclusion. As a result of repeated incisors amputation in rat submandibular glands acini and ducts epithelial cells develop reversible structural and functional changes, which are leveled by the 12th and 6th week of the experiment, respectively.https://bulletin.ssmu.ru/jour/article/view/1115гипертрофияподнижнечелюстные слюнные железыморфофункциональная характеристика
spellingShingle V. V. Ivanova
I. V. Milto
I. V. Sukhodolo
Morphological and functional state of the epithelial cells in submandibular salivary glands after repeated amputations of the incisor teeth in adult rats
Бюллетень сибирской медицины
гипертрофия
поднижнечелюстные слюнные железы
морфофункциональная характеристика
title Morphological and functional state of the epithelial cells in submandibular salivary glands after repeated amputations of the incisor teeth in adult rats
title_full Morphological and functional state of the epithelial cells in submandibular salivary glands after repeated amputations of the incisor teeth in adult rats
title_fullStr Morphological and functional state of the epithelial cells in submandibular salivary glands after repeated amputations of the incisor teeth in adult rats
title_full_unstemmed Morphological and functional state of the epithelial cells in submandibular salivary glands after repeated amputations of the incisor teeth in adult rats
title_short Morphological and functional state of the epithelial cells in submandibular salivary glands after repeated amputations of the incisor teeth in adult rats
title_sort morphological and functional state of the epithelial cells in submandibular salivary glands after repeated amputations of the incisor teeth in adult rats
topic гипертрофия
поднижнечелюстные слюнные железы
морфофункциональная характеристика
url https://bulletin.ssmu.ru/jour/article/view/1115
work_keys_str_mv AT vvivanova morphologicalandfunctionalstateoftheepithelialcellsinsubmandibularsalivaryglandsafterrepeatedamputationsoftheincisorteethinadultrats
AT ivmilto morphologicalandfunctionalstateoftheepithelialcellsinsubmandibularsalivaryglandsafterrepeatedamputationsoftheincisorteethinadultrats
AT ivsukhodolo morphologicalandfunctionalstateoftheepithelialcellsinsubmandibularsalivaryglandsafterrepeatedamputationsoftheincisorteethinadultrats