Effects of Ceftriaxone on Oxidative Stress and Inflammation in a Rat Model of Chronic Cerebral Hypoperfusion

Effects of Ceftriaxone on Oxidative Stress and Inflammation in a Rat Model of Chronic Cerebral Hypoperfusion

Ceftriaxone (CTX) exerts a neuroprotective effect by decreasing glutamate excitotoxicity. We further studied the underlying mechanisms and effects of CTX early post-treatment on behavior in a cerebral hypoperfusion rats. The rats’ common carotid arteries (2VO) were permanently ligated. CTX was treat...

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Bibliographic Details
Main Authors: Apsorn Sattayakhom, Kosin Kalarat, Thatdao Rakmak, Sompol Tapechum, Arnaud Monteil, Chuchard Punsawad, Sarawoot Palipoch, Phanit Koomhin
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Behavioral Sciences
Subjects:
ceftriaxone
white matter damage
oxidative stress
inflammation
Online Access:https://www.mdpi.com/2076-328X/12/8/287

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