Blood Samples of Cancerous Patients as Biomarkers of Alpha Emitters
Introduction: Radioactive contamination by uranium and its emissions, such as alpha particles, is considered one of the most critical issues affecting the human race and its existence. The study investigated the high ionization capacity number of alpha particles in whole blood samples from cancer pa...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2023-07-01
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| Series: | Iranian Journal of Medical Physics |
| Subjects: | |
| Online Access: | https://ijmp.mums.ac.ir/article_20777_20fd1582dff9bba0c122ee6045ab7180.pdf |
| _version_ | 1797209634375729152 |
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| author | Haura Abas SAHIB ABDUL-WAHID Adie D. Salman Salman |
| author_facet | Haura Abas SAHIB ABDUL-WAHID Adie D. Salman Salman |
| author_sort | Haura Abas |
| collection | DOAJ |
| description | Introduction: Radioactive contamination by uranium and its emissions, such as alpha particles, is considered one of the most critical issues affecting the human race and its existence. The study investigated the high ionization capacity number of alpha particles in whole blood samples from cancer patients because these particles have the most significant impact on the shape and function of living cells, modifying them into malignancies.
Material and Methods: The TASLImage solid nuclear trace detector CR-39 was used to measure the effects of alpha emitters in the whole blood samples from 40 cancer patients for five types of cancer (breast, uterus, prostate, kidney, and colon) collected from a government hospital at Karbala/Iraq and compared with ten healthy samples. Moreover, the research investigated whether smoking and gender variation affect the outcomes.
Results: The radon concentration in whole blood samples from patients and healthy individuals was significantly different (p< 0.05), and it was slightly higher in males with (22.82254±7.38794 Bq/m3). Women with colon cancer had higher blood levels of radon (32.13787±5.79261 Bq/m3) than men with the same malignancy (18.80531±5.63747 Bq/m3), regardless of gender. While the age factor had no noticeable impact, the smoking element had a considerable effect (p< 0.05).
Conclusion: All alpha levels were within the (ICRP) usual ranges. Women with colon cancer had the most significant alpha values. In contrast, men with the same disease had the lowest values despite cancer patients' blood levels being higher than those of the healthy group. |
| first_indexed | 2024-04-24T09:57:49Z |
| format | Article |
| id | doaj.art-963d25a9ce194ec6bdb5244b3170e0ac |
| institution | Directory Open Access Journal |
| issn | 2345-3672 |
| language | English |
| last_indexed | 2024-04-24T09:57:49Z |
| publishDate | 2023-07-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Medical Physics |
| spelling | doaj.art-963d25a9ce194ec6bdb5244b3170e0ac2024-04-14T06:28:23ZengMashhad University of Medical SciencesIranian Journal of Medical Physics2345-36722023-07-0120419420010.22038/ijmp.2022.64749.211120777Blood Samples of Cancerous Patients as Biomarkers of Alpha EmittersHaura Abas0SAHIB ABDUL-WAHID1Adie D. Salman Salman2Department of Physics, College of Science, University of Kerbala, 56001 Kerbala, IraqDepartment of Physics, Faculty of Education For Girls, University of Kufa, 54001 Kufa, IraqDepartment of Physics, College of Science, University of Kerbala, 56001 Kerbala, IraqIntroduction: Radioactive contamination by uranium and its emissions, such as alpha particles, is considered one of the most critical issues affecting the human race and its existence. The study investigated the high ionization capacity number of alpha particles in whole blood samples from cancer patients because these particles have the most significant impact on the shape and function of living cells, modifying them into malignancies. Material and Methods: The TASLImage solid nuclear trace detector CR-39 was used to measure the effects of alpha emitters in the whole blood samples from 40 cancer patients for five types of cancer (breast, uterus, prostate, kidney, and colon) collected from a government hospital at Karbala/Iraq and compared with ten healthy samples. Moreover, the research investigated whether smoking and gender variation affect the outcomes. Results: The radon concentration in whole blood samples from patients and healthy individuals was significantly different (p< 0.05), and it was slightly higher in males with (22.82254±7.38794 Bq/m3). Women with colon cancer had higher blood levels of radon (32.13787±5.79261 Bq/m3) than men with the same malignancy (18.80531±5.63747 Bq/m3), regardless of gender. While the age factor had no noticeable impact, the smoking element had a considerable effect (p< 0.05). Conclusion: All alpha levels were within the (ICRP) usual ranges. Women with colon cancer had the most significant alpha values. In contrast, men with the same disease had the lowest values despite cancer patients' blood levels being higher than those of the healthy group.https://ijmp.mums.ac.ir/article_20777_20fd1582dff9bba0c122ee6045ab7180.pdfalpha particleswhole bloodeffective doseradon |
| spellingShingle | Haura Abas SAHIB ABDUL-WAHID Adie D. Salman Salman Blood Samples of Cancerous Patients as Biomarkers of Alpha Emitters Iranian Journal of Medical Physics alpha particles whole blood effective dose radon |
| title | Blood Samples of Cancerous Patients as Biomarkers of Alpha Emitters |
| title_full | Blood Samples of Cancerous Patients as Biomarkers of Alpha Emitters |
| title_fullStr | Blood Samples of Cancerous Patients as Biomarkers of Alpha Emitters |
| title_full_unstemmed | Blood Samples of Cancerous Patients as Biomarkers of Alpha Emitters |
| title_short | Blood Samples of Cancerous Patients as Biomarkers of Alpha Emitters |
| title_sort | blood samples of cancerous patients as biomarkers of alpha emitters |
| topic | alpha particles whole blood effective dose radon |
| url | https://ijmp.mums.ac.ir/article_20777_20fd1582dff9bba0c122ee6045ab7180.pdf |
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