Probing the Role of Melanocortin Type 1 Receptor Agonists in Diverse Immunological Diseases

Probing the Role of Melanocortin Type 1 Receptor Agonists in Diverse Immunological Diseases

Background: The melanocortin α-melanocyte stimulating hormone (α-MSH), an endogenous peptide with high affinity for the melanocortin 1 receptor (MC1r), has demonstrated prevention and reversal of intestinal and ocular inflammation in animal models. Preclinical studies were performed to determine whe...

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Bibliographic Details
Main Authors: Carl Spana, Andrew W. Taylor, David G. Yee, Marie Makhlina, Wei Yang, John Dodd
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
melanocortin
melanocortin 1 receptor
alpha-melanocyte stimulating hormone
PL-8177
PL-8331
inflammatory bowel disease
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01535/full

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