Hepatoprotective effect of antidysbiotic drugs in experimental metabolic syndrome
Modeling of experimental metabolic syndrome in Wistar male rats was accompanied by a sharp increase in neutrophils/lymphocytes ratio and decrease in the numbers of monocytes in the blood, as well as almost 5-fold increase in the urease activity, a 3-fold decrease in the activity of lysozyme, and sig...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2017-10-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6181 |
| _version_ | 1818307663473147904 |
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| author | V. L. Vasiuk A. P. Levitsky E. M. Levchenko |
| author_facet | V. L. Vasiuk A. P. Levitsky E. M. Levchenko |
| author_sort | V. L. Vasiuk |
| collection | DOAJ |
| description | Modeling of experimental metabolic syndrome in Wistar male rats was accompanied by a sharp increase in neutrophils/lymphocytes ratio and decrease in the numbers of monocytes in the blood, as well as almost 5-fold increase in the urease activity, a 3-fold decrease in the activity of lysozyme, and significant increase in the levels of inflammatory markers (MDA and elastase) in the liver. A 13-fold increase was observed in the level of dysbiosis in the liver and a significant increase in the alkaline phosphatase activity. Using antidysbiotic drugs (Quertulin, Quertgial and lysozyme) normalized the state of liver. |
| first_indexed | 2024-12-13T07:01:57Z |
| format | Article |
| id | doaj.art-963e7a356bef4003ba535bc92acd223e |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-13T07:01:57Z |
| publishDate | 2017-10-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-963e7a356bef4003ba535bc92acd223e2022-12-21T23:55:55ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-10-0171029029710.5281/zenodo.14617345586Hepatoprotective effect of antidysbiotic drugs in experimental metabolic syndromeV. L. Vasiuk0A. P. Levitsky1E. M. Levchenko2Bukovinian State Medical UnіversityState Institution “Institute of Stomatology NAMS Ukraine”Municipal Institution “Odessa Regional Hospital”Modeling of experimental metabolic syndrome in Wistar male rats was accompanied by a sharp increase in neutrophils/lymphocytes ratio and decrease in the numbers of monocytes in the blood, as well as almost 5-fold increase in the urease activity, a 3-fold decrease in the activity of lysozyme, and significant increase in the levels of inflammatory markers (MDA and elastase) in the liver. A 13-fold increase was observed in the level of dysbiosis in the liver and a significant increase in the alkaline phosphatase activity. Using antidysbiotic drugs (Quertulin, Quertgial and lysozyme) normalized the state of liver.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6181liver, metabolic syndrome, dysbiosis, immunodeficiency, antidisbiotic drugs |
| spellingShingle | V. L. Vasiuk A. P. Levitsky E. M. Levchenko Hepatoprotective effect of antidysbiotic drugs in experimental metabolic syndrome Journal of Education, Health and Sport liver, metabolic syndrome, dysbiosis, immunodeficiency, antidisbiotic drugs |
| title | Hepatoprotective effect of antidysbiotic drugs in experimental metabolic syndrome |
| title_full | Hepatoprotective effect of antidysbiotic drugs in experimental metabolic syndrome |
| title_fullStr | Hepatoprotective effect of antidysbiotic drugs in experimental metabolic syndrome |
| title_full_unstemmed | Hepatoprotective effect of antidysbiotic drugs in experimental metabolic syndrome |
| title_short | Hepatoprotective effect of antidysbiotic drugs in experimental metabolic syndrome |
| title_sort | hepatoprotective effect of antidysbiotic drugs in experimental metabolic syndrome |
| topic | liver, metabolic syndrome, dysbiosis, immunodeficiency, antidisbiotic drugs |
| url | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6181 |
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