Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles.

Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles.

All positive strand (+RNA) viruses of eukaryotes replicate their genomes in association with membranes. The mechanisms of membrane remodeling in infected cells represent attractive targets for designing future therapeutics, but our understanding of this process is very limited. Elements of autophagy...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Jules A Nchoutmboube, Ekaterina G Viktorova, Alison J Scott, Lauren A Ford, Zhengtong Pei, Paul A Watkins, Robert K Ernst, George A Belov
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Public Library of Science (PLoS) 2013-01-01
Saila:PLoS Pathogens
Sarrera elektronikoa:http://europepmc.org/articles/PMC3675155?pdf=render

Internet

http://europepmc.org/articles/PMC3675155?pdf=render

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