Study of the relationship between Androctonus crassicauda (Oliver, 1807; scorpiones, buthidae) venom toxicity and telson size, weight and storing condition
Scorpions are included in the order Scorpiones; class Arachnida. Lethal scorpions are mostly of the Buthidae family. Among these, species belonging to Androctonus, Leiurus and Mesobuthus genera cause most scorpion envenomations in Turkey. This study was performed aiming the production of antivenom b...
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| Format: | Article |
| Language: | English |
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SciELO
2006-04-01
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| Series: | Journal of Venomous Animals and Toxins including Tropical Diseases |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000200011 |
| _version_ | 1818135258616299520 |
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| author | O. Ozkan S. Adiguzel S. Yakistiran A. Filazi |
| author_facet | O. Ozkan S. Adiguzel S. Yakistiran A. Filazi |
| author_sort | O. Ozkan |
| collection | DOAJ |
| description | Scorpions are included in the order Scorpiones; class Arachnida. Lethal scorpions are mostly of the Buthidae family. Among these, species belonging to Androctonus, Leiurus and Mesobuthus genera cause most scorpion envenomations in Turkey. This study was performed aiming the production of antivenom by using Androctonus crassicauda telsons. Venom toxicity is related to telson weight, size, and storing condition (open or closed). Telsons of A. crassicauda were collected in Southeastern Anatolia (especially in Harran town, Sanliurfa), Turkey. They were separated according to weight, size, and storing condition - open (a) and closed (b). Venom solution was prepared by maceration of telsons. Swiss albino mice were used to determine the lethal dose 50% (LD50), which was as follows: Group 1a - 2.31mg; Group 1b - 2.66mg; Group 2a - 2.32mg; Group 2b - 2.66mg; Group 3a - 6.66mg; Group 3b - 6.88mg. Among the groups of telsons, the first and the second groups showed different characteristics. However, there were no differences between their toxicity. In the third group, a fourfold amount of telsons was used for toxicity. In other words, telsons weighting from 19.99 to 20mg (first group) and from 29.99 to 30mg (second group) presented similar LD50 values, and telsons weighting from 10 to 19.99mg (third group) showed a fourfold higher LD50 value. This difference was caused by the maturity of scorpions and venom toxicity was related to their size. The first and second groups were considered to be mature and the third group, not adult. Therefore, we can conclude that obtaining open telsons due to environmental factors was not effective for venom toxicity. |
| first_indexed | 2024-12-11T09:21:39Z |
| format | Article |
| id | doaj.art-96423163a5dc43ebb5e70955993f91b3 |
| institution | Directory Open Access Journal |
| issn | 1678-9199 |
| language | English |
| last_indexed | 2024-12-11T09:21:39Z |
| publishDate | 2006-04-01 |
| publisher | SciELO |
| record_format | Article |
| series | Journal of Venomous Animals and Toxins including Tropical Diseases |
| spelling | doaj.art-96423163a5dc43ebb5e70955993f91b32022-12-22T01:13:14ZengSciELOJournal of Venomous Animals and Toxins including Tropical Diseases1678-91992006-04-0112229730910.1590/S1678-91992006000200011Study of the relationship between Androctonus crassicauda (Oliver, 1807; scorpiones, buthidae) venom toxicity and telson size, weight and storing conditionO. OzkanS. AdiguzelS. YakistiranA. FilaziScorpions are included in the order Scorpiones; class Arachnida. Lethal scorpions are mostly of the Buthidae family. Among these, species belonging to Androctonus, Leiurus and Mesobuthus genera cause most scorpion envenomations in Turkey. This study was performed aiming the production of antivenom by using Androctonus crassicauda telsons. Venom toxicity is related to telson weight, size, and storing condition (open or closed). Telsons of A. crassicauda were collected in Southeastern Anatolia (especially in Harran town, Sanliurfa), Turkey. They were separated according to weight, size, and storing condition - open (a) and closed (b). Venom solution was prepared by maceration of telsons. Swiss albino mice were used to determine the lethal dose 50% (LD50), which was as follows: Group 1a - 2.31mg; Group 1b - 2.66mg; Group 2a - 2.32mg; Group 2b - 2.66mg; Group 3a - 6.66mg; Group 3b - 6.88mg. Among the groups of telsons, the first and the second groups showed different characteristics. However, there were no differences between their toxicity. In the third group, a fourfold amount of telsons was used for toxicity. In other words, telsons weighting from 19.99 to 20mg (first group) and from 29.99 to 30mg (second group) presented similar LD50 values, and telsons weighting from 10 to 19.99mg (third group) showed a fourfold higher LD50 value. This difference was caused by the maturity of scorpions and venom toxicity was related to their size. The first and second groups were considered to be mature and the third group, not adult. Therefore, we can conclude that obtaining open telsons due to environmental factors was not effective for venom toxicity.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000200011scorpionAndroctonus crassicauda (Oliver, 1807)telson size and weightLD50, acute toxicity |
| spellingShingle | O. Ozkan S. Adiguzel S. Yakistiran A. Filazi Study of the relationship between Androctonus crassicauda (Oliver, 1807; scorpiones, buthidae) venom toxicity and telson size, weight and storing condition Journal of Venomous Animals and Toxins including Tropical Diseases scorpion Androctonus crassicauda (Oliver, 1807) telson size and weight LD50, acute toxicity |
| title | Study of the relationship between Androctonus crassicauda (Oliver, 1807; scorpiones, buthidae) venom toxicity and telson size, weight and storing condition |
| title_full | Study of the relationship between Androctonus crassicauda (Oliver, 1807; scorpiones, buthidae) venom toxicity and telson size, weight and storing condition |
| title_fullStr | Study of the relationship between Androctonus crassicauda (Oliver, 1807; scorpiones, buthidae) venom toxicity and telson size, weight and storing condition |
| title_full_unstemmed | Study of the relationship between Androctonus crassicauda (Oliver, 1807; scorpiones, buthidae) venom toxicity and telson size, weight and storing condition |
| title_short | Study of the relationship between Androctonus crassicauda (Oliver, 1807; scorpiones, buthidae) venom toxicity and telson size, weight and storing condition |
| title_sort | study of the relationship between androctonus crassicauda oliver 1807 scorpiones buthidae venom toxicity and telson size weight and storing condition |
| topic | scorpion Androctonus crassicauda (Oliver, 1807) telson size and weight LD50, acute toxicity |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000200011 |
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