Skeletal muscle mitoribosomal defects are linked to low bone mass caused by bone marrow inflammation in male mice

Abstract Background Mitochondrial oxidative phosphorylation (OxPhos) is a critical regulator of skeletal muscle mass and function. Although muscle atrophy due to mitochondrial dysfunction is closely associated with bone loss, the biological characteristics of the relationship between muscle and bone...

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Main Authors: Jingwen Tian, Hyo Kyun Chung, Ji Sun Moon, Ha Thi Nga, Ho Yeop Lee, Jung Tae Kim, Joon Young Chang, Seul Gi Kang, Dongryeol Ryu, Xiangguo Che, Je‐Yong Choi, Masayuki Tsukasaki, Takayoshi Sasako, Sang‐Hee Lee, Minho Shong, Hyon‐Seung Yi
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Online Access:https://doi.org/10.1002/jcsm.12975