Direct measurement of pervasive weak repression by microRNAs and their role at the network level
Abstract Background A gene regulatory network (GRN) comprises many weak links that are often regulated by microRNAs. Since miRNAs rarely repress their target genes by more than 30%, doubts have been expressed about the biological relevance of such weak effects. These doubts raise the possibility of...
Main Authors: | Fuqiang Ma, Pei Lin, Qingjian Chen, Xuemei Lu, Yong E. Zhang, Chung-I Wu |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-05-01
|
Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-018-4757-z |
Similar Items
-
MicroRNAs that target RGS5
by: Amir Banaei-Esfahani, et al.
Published: (2015-02-01) -
The Role of microRNAs in Pulp Inflammation
by: José Luis Muñoz-Carrillo, et al.
Published: (2021-08-01) -
MicroRNAs in the Mouse Developing Retina
by: Jorge Navarro-Calvo, et al.
Published: (2023-02-01) -
The roles of rice microRNAs in rice-Magnaporthe oryzae interaction
by: Yan Li, et al.
Published: (2019-11-01) -
Mechanisms of action of cytoplasmic microRNAs. Part 1. Mechanisms of interaction of microRNA and mRNA molecules. Influence of microRNAs on translation
by: A.E. Abaturov, et al.
Published: (2022-04-01)