Synapse‐selective rapid potentiation of hippocampal synaptic transmission by 7,8‐dihydroxyflavone

Abstract Aim The identification of 7,8‐dihydroxyflavone (DHF) as a small molecule agonist for tropomyosin‐related kinase B (TrkB) facilitated understanding of the role of TrkB signaling in regulating higher brain functions. DHF can penetrate the blood‐brain barrier after systemic administration and...

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Bibliographic Details
Main Authors: Katsunori Kobayashi, Hidenori Suzuki
Format: Article
Language:English
Published: Wiley 2018-12-01
Series:Neuropsychopharmacology Reports
Subjects:
Online Access:https://doi.org/10.1002/npr2.12033