HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL
In experimental liver pathology caused by isoniazide or paracetamol administration to albino rats lipids derived from maral antlers and peat decreased the blood activity of aminotransferases, γ-glutamyltranspeptidase, acid and alkaline phosphatases, phospholipase А, content of common bilirubin, acti...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Siberian State Medical University (Tomsk)
2013-02-01
|
Series: | Бюллетень сибирской медицины |
Subjects: | |
Online Access: | https://bulletin.ssmu.ru/jour/article/view/43 |
_version_ | 1797872981681111040 |
---|---|
author | A. I. Yatsenkov |
author_facet | A. I. Yatsenkov |
author_sort | A. I. Yatsenkov |
collection | DOAJ |
description | In experimental liver pathology caused by isoniazide or paracetamol administration to albino rats lipids derived from maral antlers and peat decreased the blood activity of aminotransferases, γ-glutamyltranspeptidase, acid and alkaline phosphatases, phospholipase А, content of common bilirubin, activated the detoxication of biliribin, ammonium and phenols, inhibited the liver formation of dienic conjugates, Schiff’s bases, malonic dialdehyde, improve the reduced glutathione function. Maral anthlers and peat lipids in effective doses 30 and 60 mg/kg had the more pronounced hepatoprotective and antioxidant action than lipids in dose 10 mg/kg and essentiale forte N. |
first_indexed | 2024-04-10T01:08:53Z |
format | Article |
id | doaj.art-964a109fef994873bff3767c0fd8b12e |
institution | Directory Open Access Journal |
issn | 1682-0363 1819-3684 |
language | English |
last_indexed | 2024-04-10T01:08:53Z |
publishDate | 2013-02-01 |
publisher | Siberian State Medical University (Tomsk) |
record_format | Article |
series | Бюллетень сибирской медицины |
spelling | doaj.art-964a109fef994873bff3767c0fd8b12e2023-03-13T09:58:18ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842013-02-01121808510.20538/1682-0363-2013-1-80-8543HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOLA. I. Yatsenkov0Сибирский государственный медицинский университет, ТомскIn experimental liver pathology caused by isoniazide or paracetamol administration to albino rats lipids derived from maral antlers and peat decreased the blood activity of aminotransferases, γ-glutamyltranspeptidase, acid and alkaline phosphatases, phospholipase А, content of common bilirubin, activated the detoxication of biliribin, ammonium and phenols, inhibited the liver formation of dienic conjugates, Schiff’s bases, malonic dialdehyde, improve the reduced glutathione function. Maral anthlers and peat lipids in effective doses 30 and 60 mg/kg had the more pronounced hepatoprotective and antioxidant action than lipids in dose 10 mg/kg and essentiale forte N.https://bulletin.ssmu.ru/jour/article/view/43печеньэкспериментальная патологияизониазидпарацетамоллипиды пан-тов маралалипиды торфагепатопротективное действие |
spellingShingle | A. I. Yatsenkov HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL Бюллетень сибирской медицины печень экспериментальная патология изониазид парацетамол липиды пан-тов марала липиды торфа гепатопротективное действие |
title | HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL |
title_full | HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL |
title_fullStr | HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL |
title_full_unstemmed | HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL |
title_short | HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL |
title_sort | hepatoprotective action of polar lipids of maral antlers and peat in experimental liver damage caused by isoniazide and paracetamol |
topic | печень экспериментальная патология изониазид парацетамол липиды пан-тов марала липиды торфа гепатопротективное действие |
url | https://bulletin.ssmu.ru/jour/article/view/43 |
work_keys_str_mv | AT aiyatsenkov hepatoprotectiveactionofpolarlipidsofmaralantlersandpeatinexperimentalliverdamagecausedbyisoniazideandparacetamol |