HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL

In experimental liver pathology caused by isoniazide or paracetamol administration to albino rats lipids derived from maral antlers and peat decreased the blood activity of aminotransferases, γ-glutamyltranspeptidase, acid and alkaline phosphatases, phospholipase А, content of common bilirubin, acti...

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Main Author: A. I. Yatsenkov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2013-02-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/43
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author A. I. Yatsenkov
author_facet A. I. Yatsenkov
author_sort A. I. Yatsenkov
collection DOAJ
description In experimental liver pathology caused by isoniazide or paracetamol administration to albino rats lipids derived from maral antlers and peat decreased the blood activity of aminotransferases, γ-glutamyltranspeptidase, acid and alkaline phosphatases, phospholipase А, content of common bilirubin, activated the detoxication of biliribin, ammonium and phenols, inhibited the liver formation of dienic conjugates, Schiff’s bases, malonic dialdehyde, improve the reduced glutathione function. Maral anthlers and peat lipids in effective doses 30 and 60 mg/kg had the more pronounced hepatoprotective and antioxidant action than lipids in dose 10 mg/kg and essentiale forte N.
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spelling doaj.art-964a109fef994873bff3767c0fd8b12e2023-03-13T09:58:18ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842013-02-01121808510.20538/1682-0363-2013-1-80-8543HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOLA. I. Yatsenkov0Сибирский государственный медицинский университет, ТомскIn experimental liver pathology caused by isoniazide or paracetamol administration to albino rats lipids derived from maral antlers and peat decreased the blood activity of aminotransferases, γ-glutamyltranspeptidase, acid and alkaline phosphatases, phospholipase А, content of common bilirubin, activated the detoxication of biliribin, ammonium and phenols, inhibited the liver formation of dienic conjugates, Schiff’s bases, malonic dialdehyde, improve the reduced glutathione function. Maral anthlers and peat lipids in effective doses 30 and 60 mg/kg had the more pronounced hepatoprotective and antioxidant action than lipids in dose 10 mg/kg and essentiale forte N.https://bulletin.ssmu.ru/jour/article/view/43печеньэкспериментальная патологияизониазидпарацетамоллипиды пан-тов маралалипиды торфагепатопротективное действие
spellingShingle A. I. Yatsenkov
HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL
Бюллетень сибирской медицины
печень
экспериментальная патология
изониазид
парацетамол
липиды пан-тов марала
липиды торфа
гепатопротективное действие
title HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL
title_full HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL
title_fullStr HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL
title_full_unstemmed HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL
title_short HEPATOPROTECTIVE ACTION OF POLAR LIPIDS OF MARAL ANTLERS AND PEAT IN EXPERIMENTAL LIVER DAMAGE CAUSED BY ISONIAZIDE AND PARACETAMOL
title_sort hepatoprotective action of polar lipids of maral antlers and peat in experimental liver damage caused by isoniazide and paracetamol
topic печень
экспериментальная патология
изониазид
парацетамол
липиды пан-тов марала
липиды торфа
гепатопротективное действие
url https://bulletin.ssmu.ru/jour/article/view/43
work_keys_str_mv AT aiyatsenkov hepatoprotectiveactionofpolarlipidsofmaralantlersandpeatinexperimentalliverdamagecausedbyisoniazideandparacetamol