Сlinical and biochemical assessment of dynamics of an acute period of brain injury and combined cranio-facial injury
The purpose of the study was to assess clinical effects anddynamics of the changes in the parameters of lipid peroxidationand antioxidant system in patients with acute traumatic braininjury and combined injuries treated with the peptide drug cortexin.As the result of this work, the ability of the dr...
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| Format: | Article |
| Language: | English |
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Research Center of Neurology
2017-02-01
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| Series: | Анналы клинической и экспериментальной неврологии |
| Subjects: | |
| Online Access: | https://annaly-nevrologii.com/journal/pathID/article/viewFile/220/51 |
| _version_ | 1818240585445670912 |
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| author | V. A. Sadova G. N. Bel’skaya E. I. L’vovskaya D. G. Kuchin I. A. Atmansky V. Y. Shkarednykh D. B. Sumnaya |
| author_facet | V. A. Sadova G. N. Bel’skaya E. I. L’vovskaya D. G. Kuchin I. A. Atmansky V. Y. Shkarednykh D. B. Sumnaya |
| author_sort | V. A. Sadova |
| collection | DOAJ |
| description | The purpose of the study was to assess clinical effects anddynamics of the changes in the parameters of lipid peroxidationand antioxidant system in patients with acute traumatic braininjury and combined injuries treated with the peptide drug cortexin.As the result of this work, the ability of the drug to reducethe intensity of the of lipid peroxidation process in brain injurywas revealed. Clinical effect was expressed by the reduction ofasthenic symptoms, significant improvement of attention andmemory, and increase of the working capacity and the tempo ofmental activity, which was confirmed by psychometric tests. Itwas shown that cortexin use in an acute period of traumatic braininjury and combined cranio-facial injury significantly increasedthe patients quality of life, had sedative and antidepressanteffect, reduced epileptic activity and decreased the frequency ofepileptic seizures. |
| first_indexed | 2024-12-12T13:15:47Z |
| format | Article |
| id | doaj.art-964a590e1b6f47779ebbcda67d852b0f |
| institution | Directory Open Access Journal |
| issn | 2075-5473 2409-2533 |
| language | English |
| last_indexed | 2024-12-12T13:15:47Z |
| publishDate | 2017-02-01 |
| publisher | Research Center of Neurology |
| record_format | Article |
| series | Анналы клинической и экспериментальной неврологии |
| spelling | doaj.art-964a590e1b6f47779ebbcda67d852b0f2022-12-22T00:23:25ZengResearch Center of NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-25332017-02-0174273110.17816/psaic220113Сlinical and biochemical assessment of dynamics of an acute period of brain injury and combined cranio-facial injuryV. A. Sadova0G. N. Bel’skaya1E. I. L’vovskaya2D. G. Kuchin3I. A. Atmansky4V. Y. Shkarednykh5D. B. Sumnaya6Ural State University of Physical CultureSouth-Ural State UniversitUral State University of Physical CultureStomatological Out-patient Clinic № 1South-Ural State Medical UniversityChelyabinsk Regional Clinical Hospital № 3Ural State University of Physical CultureThe purpose of the study was to assess clinical effects anddynamics of the changes in the parameters of lipid peroxidationand antioxidant system in patients with acute traumatic braininjury and combined injuries treated with the peptide drug cortexin.As the result of this work, the ability of the drug to reducethe intensity of the of lipid peroxidation process in brain injurywas revealed. Clinical effect was expressed by the reduction ofasthenic symptoms, significant improvement of attention andmemory, and increase of the working capacity and the tempo ofmental activity, which was confirmed by psychometric tests. Itwas shown that cortexin use in an acute period of traumatic braininjury and combined cranio-facial injury significantly increasedthe patients quality of life, had sedative and antidepressanteffect, reduced epileptic activity and decreased the frequency ofepileptic seizures.https://annaly-nevrologii.com/journal/pathID/article/viewFile/220/51traumatic brain injurycombined cranio-facial injurylipid peroxidationantioxidant systemcortexin |
| spellingShingle | V. A. Sadova G. N. Bel’skaya E. I. L’vovskaya D. G. Kuchin I. A. Atmansky V. Y. Shkarednykh D. B. Sumnaya Сlinical and biochemical assessment of dynamics of an acute period of brain injury and combined cranio-facial injury Анналы клинической и экспериментальной неврологии traumatic brain injury combined cranio-facial injury lipid peroxidation antioxidant system cortexin |
| title | Сlinical and biochemical assessment of dynamics of an acute period of brain injury and combined cranio-facial injury |
| title_full | Сlinical and biochemical assessment of dynamics of an acute period of brain injury and combined cranio-facial injury |
| title_fullStr | Сlinical and biochemical assessment of dynamics of an acute period of brain injury and combined cranio-facial injury |
| title_full_unstemmed | Сlinical and biochemical assessment of dynamics of an acute period of brain injury and combined cranio-facial injury |
| title_short | Сlinical and biochemical assessment of dynamics of an acute period of brain injury and combined cranio-facial injury |
| title_sort | сlinical and biochemical assessment of dynamics of an acute period of brain injury and combined cranio facial injury |
| topic | traumatic brain injury combined cranio-facial injury lipid peroxidation antioxidant system cortexin |
| url | https://annaly-nevrologii.com/journal/pathID/article/viewFile/220/51 |
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