Electrospun Magnetic Ionic Liquid Based Electroactive Materials for Tissue Engineering Applications
Functional electrospun fibers incorporating ionic liquids (ILs) present a novel approach in the development of active microenviroments due to their ability to respond to external magnetic fields without the addition of magnetic particles. In this context, this work reports on the development of magn...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/17/3072 |
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| author | Liliana C. Fernandes Rafaela M. Meira Daniela M. Correia Clarisse Ribeiro Eduardo Fernandez Carmen R. Tubio Senentxu Lanceros-Méndez |
| author_facet | Liliana C. Fernandes Rafaela M. Meira Daniela M. Correia Clarisse Ribeiro Eduardo Fernandez Carmen R. Tubio Senentxu Lanceros-Méndez |
| author_sort | Liliana C. Fernandes |
| collection | DOAJ |
| description | Functional electrospun fibers incorporating ionic liquids (ILs) present a novel approach in the development of active microenviroments due to their ability to respond to external magnetic fields without the addition of magnetic particles. In this context, this work reports on the development of magnetically responsive magneto-ionic fibers based on the electroactive polymer poly(vinylidene fluoride) and the magnetic IL (MIL), bis(1-butyl-3-methylimidazolium) tetrathiocyanatocobaltate ([Bmim]<sub>2</sub>[(SCN)<sub>4</sub>Co]). The PVDF/MIL electrospun fibers were prepared incorporating 5, 10 and 15 wt.% of the MIL, showing that the inclusion of the MIL increases the polar <i>β</i>-phase content of the polymer from 79% to 94% and decreases the crystallinity of the fibers from 47% to 36%. Furthermore, the thermal stability of the fibers decreases with the incorporation of the MIL. The magnetization of the PVDF/MIL composite fibers is proportional to the MIL content and decreases with temperature. Finally, cytotoxicity assays show a decrease in cell viability with increasing the MIL content. |
| first_indexed | 2024-03-10T01:26:57Z |
| format | Article |
| id | doaj.art-964ffee9e5654afe82df57db92882b8a |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T01:26:57Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-964ffee9e5654afe82df57db92882b8a2023-11-23T13:50:24ZengMDPI AGNanomaterials2079-49912022-09-011217307210.3390/nano12173072Electrospun Magnetic Ionic Liquid Based Electroactive Materials for Tissue Engineering ApplicationsLiliana C. Fernandes0Rafaela M. Meira1Daniela M. Correia2Clarisse Ribeiro3Eduardo Fernandez4Carmen R. Tubio5Senentxu Lanceros-Méndez6Physics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, 4710-057 Braga, PortugalPhysics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, 4710-057 Braga, PortugalCentre of Chemistry, University of Minho, 4710-057 Braga, PortugalPhysics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, 4710-057 Braga, PortugalBCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940 Leioa, SpainBCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940 Leioa, SpainBCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940 Leioa, SpainFunctional electrospun fibers incorporating ionic liquids (ILs) present a novel approach in the development of active microenviroments due to their ability to respond to external magnetic fields without the addition of magnetic particles. In this context, this work reports on the development of magnetically responsive magneto-ionic fibers based on the electroactive polymer poly(vinylidene fluoride) and the magnetic IL (MIL), bis(1-butyl-3-methylimidazolium) tetrathiocyanatocobaltate ([Bmim]<sub>2</sub>[(SCN)<sub>4</sub>Co]). The PVDF/MIL electrospun fibers were prepared incorporating 5, 10 and 15 wt.% of the MIL, showing that the inclusion of the MIL increases the polar <i>β</i>-phase content of the polymer from 79% to 94% and decreases the crystallinity of the fibers from 47% to 36%. Furthermore, the thermal stability of the fibers decreases with the incorporation of the MIL. The magnetization of the PVDF/MIL composite fibers is proportional to the MIL content and decreases with temperature. Finally, cytotoxicity assays show a decrease in cell viability with increasing the MIL content.https://www.mdpi.com/2079-4991/12/17/3072electrospun fiberselectroactive materialspiezoelectric polymersionic liquidstissue engineering |
| spellingShingle | Liliana C. Fernandes Rafaela M. Meira Daniela M. Correia Clarisse Ribeiro Eduardo Fernandez Carmen R. Tubio Senentxu Lanceros-Méndez Electrospun Magnetic Ionic Liquid Based Electroactive Materials for Tissue Engineering Applications Nanomaterials electrospun fibers electroactive materials piezoelectric polymers ionic liquids tissue engineering |
| title | Electrospun Magnetic Ionic Liquid Based Electroactive Materials for Tissue Engineering Applications |
| title_full | Electrospun Magnetic Ionic Liquid Based Electroactive Materials for Tissue Engineering Applications |
| title_fullStr | Electrospun Magnetic Ionic Liquid Based Electroactive Materials for Tissue Engineering Applications |
| title_full_unstemmed | Electrospun Magnetic Ionic Liquid Based Electroactive Materials for Tissue Engineering Applications |
| title_short | Electrospun Magnetic Ionic Liquid Based Electroactive Materials for Tissue Engineering Applications |
| title_sort | electrospun magnetic ionic liquid based electroactive materials for tissue engineering applications |
| topic | electrospun fibers electroactive materials piezoelectric polymers ionic liquids tissue engineering |
| url | https://www.mdpi.com/2079-4991/12/17/3072 |
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