Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS study
<p>Abstract</p> <p>Background</p> <p>Hypercholesterolemia is one of the most important factors causing cardiovascular disease (CVD). The aim of the present work was to evaluate the relationships between socio-demographic, clinical, lifestyle and depression status and th...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2009-03-01
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| Series: | Lipids in Health and Disease |
| Online Access: | http://www.lipidworld.com/content/8/1/10 |
| _version_ | 1818035988137508864 |
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| author | Makri Kornilia Metallinos George Papairakleous Natassa Katsarou Alexia Micheli Mary Bountziouka Vassiliki Zeimbekis Akis Lionis Christos Tyrovolas Stefanos Polychronopoulos Evangelos Panagiotakos Demosthenes B |
| author_facet | Makri Kornilia Metallinos George Papairakleous Natassa Katsarou Alexia Micheli Mary Bountziouka Vassiliki Zeimbekis Akis Lionis Christos Tyrovolas Stefanos Polychronopoulos Evangelos Panagiotakos Demosthenes B |
| author_sort | Makri Kornilia |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Hypercholesterolemia is one of the most important factors causing cardiovascular disease (CVD). The aim of the present work was to evaluate the relationships between socio-demographic, clinical, lifestyle and depression status and the presence of hypercholesterolemia, among elderly individuals without known CVD.</p> <p>Methods</p> <p>During 2005–2007, 1190 elderly (aged 65 to 100 years) men and women (from Cyprus, Mitilini, Samothraki, Cephalonia, Crete, Lemnos, Corfu and Zakynthos) were enrolled. Socio-demographic, clinical and lifestyle factors were assessed through standard procedures. Symptoms of depression were evaluated using the short-form of the Geriatric Depression Scale (GDS, range 0–15). Dietary habits were assessed through a semi-quantitative food frequency questionnaire. Hypercholesterolemia was defined as total serum cholesterol > 200 mg/dL or use of lipids lowering medication.</p> <p>Results</p> <p>44.6% of males and 61.9% of females had hypercholesterolemia (p < 0.001). Only, 63% of hypercholesterolemic participants were under special diet or pharmaceutical treatment. Hypercholisterolemic individuals had higher prevalence of obesity (43% vs. 25%), hypertension (76% vs. 57%) and diabetes (25% vs. 17%) compared with normal participants (p < 0.001). Furthermore, hypercholisterolemic participants showed higher depression levels (p = 0.002). After adjusting for various confounders, GDS score and BMI correlated with 13% (95%CI 0.98–1.30) and 14% (95%CI 0.99–1.31) higher likelihood of having hypercholesterolemia.</p> <p>Conclusion</p> <p>A considerable proportion of our elderly sample had hypercholesterolemia, while 1/3 of them were untreated. Furthermore, presence of hypercholesterolemia was correlated with depressive symptomatology and increased BMI.</p> |
| first_indexed | 2024-12-10T07:03:48Z |
| format | Article |
| id | doaj.art-96521889e0154a4289ba9b2a0f3a4fac |
| institution | Directory Open Access Journal |
| issn | 1476-511X |
| language | English |
| last_indexed | 2024-12-10T07:03:48Z |
| publishDate | 2009-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Lipids in Health and Disease |
| spelling | doaj.art-96521889e0154a4289ba9b2a0f3a4fac2022-12-22T01:58:15ZengBMCLipids in Health and Disease1476-511X2009-03-01811010.1186/1476-511X-8-10Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS studyMakri KorniliaMetallinos GeorgePapairakleous NatassaKatsarou AlexiaMicheli MaryBountziouka VassilikiZeimbekis AkisLionis ChristosTyrovolas StefanosPolychronopoulos EvangelosPanagiotakos Demosthenes B<p>Abstract</p> <p>Background</p> <p>Hypercholesterolemia is one of the most important factors causing cardiovascular disease (CVD). The aim of the present work was to evaluate the relationships between socio-demographic, clinical, lifestyle and depression status and the presence of hypercholesterolemia, among elderly individuals without known CVD.</p> <p>Methods</p> <p>During 2005–2007, 1190 elderly (aged 65 to 100 years) men and women (from Cyprus, Mitilini, Samothraki, Cephalonia, Crete, Lemnos, Corfu and Zakynthos) were enrolled. Socio-demographic, clinical and lifestyle factors were assessed through standard procedures. Symptoms of depression were evaluated using the short-form of the Geriatric Depression Scale (GDS, range 0–15). Dietary habits were assessed through a semi-quantitative food frequency questionnaire. Hypercholesterolemia was defined as total serum cholesterol > 200 mg/dL or use of lipids lowering medication.</p> <p>Results</p> <p>44.6% of males and 61.9% of females had hypercholesterolemia (p < 0.001). Only, 63% of hypercholesterolemic participants were under special diet or pharmaceutical treatment. Hypercholisterolemic individuals had higher prevalence of obesity (43% vs. 25%), hypertension (76% vs. 57%) and diabetes (25% vs. 17%) compared with normal participants (p < 0.001). Furthermore, hypercholisterolemic participants showed higher depression levels (p = 0.002). After adjusting for various confounders, GDS score and BMI correlated with 13% (95%CI 0.98–1.30) and 14% (95%CI 0.99–1.31) higher likelihood of having hypercholesterolemia.</p> <p>Conclusion</p> <p>A considerable proportion of our elderly sample had hypercholesterolemia, while 1/3 of them were untreated. Furthermore, presence of hypercholesterolemia was correlated with depressive symptomatology and increased BMI.</p>http://www.lipidworld.com/content/8/1/10 |
| spellingShingle | Makri Kornilia Metallinos George Papairakleous Natassa Katsarou Alexia Micheli Mary Bountziouka Vassiliki Zeimbekis Akis Lionis Christos Tyrovolas Stefanos Polychronopoulos Evangelos Panagiotakos Demosthenes B Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS study Lipids in Health and Disease |
| title | Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS study |
| title_full | Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS study |
| title_fullStr | Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS study |
| title_full_unstemmed | Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS study |
| title_short | Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS study |
| title_sort | increased body mass and depressive symptomatology are associated with hypercholesterolemia among elderly individuals results from the medis study |
| url | http://www.lipidworld.com/content/8/1/10 |
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