Identifying Patterns of Self-Reported Nonadherence Using Network Analysis in a Mixed German Cohort

Tino Prell,1 Gabriele Helga Franke,2 Melanie Jagla-Franke,2,3 Aline Schönenberg1 1Department of Geriatrics, Halle University Hospital, Halle, Germany; 2Department of Psychology of Rehabilitation, University of Applied Sciences Magdeburg-Stendal, Magdeburg-Stendal, Germany; 3Department of Psychology...

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Main Authors: Prell T, Franke GH, Jagla-Franke M, Schönenberg A
Format: Article
Language:English
Published: Dove Medical Press 2022-05-01
Series:Patient Preference and Adherence
Subjects:
Online Access:https://www.dovepress.com/identifying-patterns-of-self-reported-nonadherence-using-network-analy-peer-reviewed-fulltext-article-PPA
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author Prell T
Franke GH
Jagla-Franke M
Schönenberg A
author_facet Prell T
Franke GH
Jagla-Franke M
Schönenberg A
author_sort Prell T
collection DOAJ
description Tino Prell,1 Gabriele Helga Franke,2 Melanie Jagla-Franke,2,3 Aline Schönenberg1 1Department of Geriatrics, Halle University Hospital, Halle, Germany; 2Department of Psychology of Rehabilitation, University of Applied Sciences Magdeburg-Stendal, Magdeburg-Stendal, Germany; 3Department of Psychology in Health Promotion and Prevention, University of Applied Sciences Neubrandenburg, Neubrandenburg, GermanyCorrespondence: Aline Schönenberg, Department of Geriatrics, Halle University Hospital, Halle, Germany, Tel +49 345 5574071, Email aline.schoenenberg@uk-halle.dePurpose: Nonadherence is a complex behaviour that contributes to poor health outcomes; therefore, it is necessary to understand its underlying structure. Network analysis is a novel approach to explore the relationship between multiple variables.Patients and Methods: Patients from four different studies (N = 1.746) using the self-reported Stendal Adherence to Medication Score (SAMS) were pooled. Network analysis using EBICglasso followed by confirmatory factor analysis were performed to understand how different types of nonadherence covered in the SAMS items are related to each other.Results: Network analysis revealed different categories of nonadherence: lack of knowledge about medication, forgetting to take medication, and intentional modification of medication. The intentional modification can further be sub-categorized into two groups, with one group modifying medication based on changes in health (improvement of health or adverse effects), whereas the second group adjusts medication based on overall medication beliefs and concerns. Adverse effects and taking too many medications were further identified as most influential variables in the network.Conclusion: The differentiation between modification due to health changes and modification due to overall medication beliefs is crucial for intervention studies. Network analysis is a promising tool for further exploratory studies of adherence.Keywords: medication adherence, older adults, polypharmacy, Stendal adherence to medication score, network analysis
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spelling doaj.art-9652b07bcd8b438592121121e2cd39682022-12-22T03:24:52ZengDove Medical PressPatient Preference and Adherence1177-889X2022-05-01Volume 161153116274997Identifying Patterns of Self-Reported Nonadherence Using Network Analysis in a Mixed German CohortPrell TFranke GHJagla-Franke MSchönenberg ATino Prell,1 Gabriele Helga Franke,2 Melanie Jagla-Franke,2,3 Aline Schönenberg1 1Department of Geriatrics, Halle University Hospital, Halle, Germany; 2Department of Psychology of Rehabilitation, University of Applied Sciences Magdeburg-Stendal, Magdeburg-Stendal, Germany; 3Department of Psychology in Health Promotion and Prevention, University of Applied Sciences Neubrandenburg, Neubrandenburg, GermanyCorrespondence: Aline Schönenberg, Department of Geriatrics, Halle University Hospital, Halle, Germany, Tel +49 345 5574071, Email aline.schoenenberg@uk-halle.dePurpose: Nonadherence is a complex behaviour that contributes to poor health outcomes; therefore, it is necessary to understand its underlying structure. Network analysis is a novel approach to explore the relationship between multiple variables.Patients and Methods: Patients from four different studies (N = 1.746) using the self-reported Stendal Adherence to Medication Score (SAMS) were pooled. Network analysis using EBICglasso followed by confirmatory factor analysis were performed to understand how different types of nonadherence covered in the SAMS items are related to each other.Results: Network analysis revealed different categories of nonadherence: lack of knowledge about medication, forgetting to take medication, and intentional modification of medication. The intentional modification can further be sub-categorized into two groups, with one group modifying medication based on changes in health (improvement of health or adverse effects), whereas the second group adjusts medication based on overall medication beliefs and concerns. Adverse effects and taking too many medications were further identified as most influential variables in the network.Conclusion: The differentiation between modification due to health changes and modification due to overall medication beliefs is crucial for intervention studies. Network analysis is a promising tool for further exploratory studies of adherence.Keywords: medication adherence, older adults, polypharmacy, Stendal adherence to medication score, network analysishttps://www.dovepress.com/identifying-patterns-of-self-reported-nonadherence-using-network-analy-peer-reviewed-fulltext-article-PPAmedication adherenceolder adultspolypharmacystendal adherence to medication scorenetwork analysis
spellingShingle Prell T
Franke GH
Jagla-Franke M
Schönenberg A
Identifying Patterns of Self-Reported Nonadherence Using Network Analysis in a Mixed German Cohort
Patient Preference and Adherence
medication adherence
older adults
polypharmacy
stendal adherence to medication score
network analysis
title Identifying Patterns of Self-Reported Nonadherence Using Network Analysis in a Mixed German Cohort
title_full Identifying Patterns of Self-Reported Nonadherence Using Network Analysis in a Mixed German Cohort
title_fullStr Identifying Patterns of Self-Reported Nonadherence Using Network Analysis in a Mixed German Cohort
title_full_unstemmed Identifying Patterns of Self-Reported Nonadherence Using Network Analysis in a Mixed German Cohort
title_short Identifying Patterns of Self-Reported Nonadherence Using Network Analysis in a Mixed German Cohort
title_sort identifying patterns of self reported nonadherence using network analysis in a mixed german cohort
topic medication adherence
older adults
polypharmacy
stendal adherence to medication score
network analysis
url https://www.dovepress.com/identifying-patterns-of-self-reported-nonadherence-using-network-analy-peer-reviewed-fulltext-article-PPA
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