Oral contraceptives modify DNA methylation and monocyte-derived macrophage function

Oral contraceptives modify DNA methylation and monocyte-derived macrophage function

<p>Abstract</p> <p>Background</p> <p>Fertile women may be encouraged to use contraception during clinical trials to avoid potential drug effects on fetuses. However, hormonal contraception interferes with pharmacokinetics and pharmacodynamics and modifies internal milie...

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Bibliographic Details
Main Authors: Campesi Ilaria, Sanna Manuela, Zinellu Angelo, Carru Ciriaco, Rubattu Laura, Bulzomi Pamela, Seghieri Giuseppe, Tonolo Giancarlo, Palermo Mario, Rosano Giuseppe, Marino Maria, Franconi Flavia
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Biology of Sex Differences
Subjects:
androgenic and non-androgenic progestin
combined oral contraceptive
estrogen receptors
global DNA methylation
monocyte-derived macrophages
TNFα
Online Access:http://www.bsd-journal.com/content/3/1/4

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