P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer

P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer

Recurrent chronic mucosal inflammation, a characteristic of inflammatory bowel diseases (IBD), perturbs the intestinal epithelial homeostasis resulting in formation of mucosal wounds and, in most severe cases, leads to colitis-associated colon cancer (CAC). The altered structure of epithelial cell-c...

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Bibliographic Details
Main Authors: Nayden G. Naydenov, Susana Lechuga, Ajay Zalavadia, Pranab K. Mukherjee, Ilyssa O. Gordon, David Skvasik, Petra Vidovic, Emina Huang, Florian Rieder, Andrei I. Ivanov
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
epithelial cells
cell migration
mucosal restitution
colon cancer
cell-cell adhesions
cadherins
Online Access:https://www.mdpi.com/2073-4409/11/9/1467

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