Differential roles of CaMKII isoforms in phase separation with NMDA receptors and in synaptic plasticity
Summary: Calcium calmodulin-dependent kinase II (CaMKII) is critical for synaptic transmission and plasticity. Two major isoforms of CaMKII, CaMKIIα and CaMKIIβ, play distinct roles in synaptic transmission and long-term potentiation (LTP) with unknown mechanisms. Here, we show that the length of th...
Main Authors: | Qixu Cai, Xiumin Chen, Shihan Zhu, Roger A. Nicoll, Mingjie Zhang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-03-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723001572 |
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