First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria
Bacteria-derived polycationic homopoly(amino acid)s are reported for the first time to directly penetrate cell membrane and deliver proteins of interest into cells, representing a new type of cell penetrating peptides for intracellular delivery.
Bibliographic Details
Main Authors: |
Yamato Takeuchi,
Kazunori Ushimaru,
Kohei Kaneda,
Chitose Maruyama,
Takashi Ito,
Kazuya Yamanaka,
Yasushi Ogasawara,
Hajime Katano,
Yasuo Kato,
Tohru Dairi,
Yoshimitsu Hamano |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2022-10-01
|
Series: | Communications Biology
|
Online Access: | https://doi.org/10.1038/s42003-022-04110-4
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