Food Monitoring: Limitations of Accelerated Storage to Predict Molecular Changes in Hazelnuts (<i>Corylus avellana</i> <span style="font-variant: small-caps">L</span>.) under Realistic Conditions Using UPLC-ESI-IM-QTOF-MS
Accelerated storage is routinely used with pharmaceuticals to predict stability and degradation patterns over time. The aim of this is to assess the shelf life and quality under harsher conditions, providing crucial insights into their long-term stability and potential storage issues. This study exp...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Metabolites |
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| Online Access: | https://www.mdpi.com/2218-1989/13/10/1031 |
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| author | Henri Loesel Navid Shakiba Soeren Wenck Phat Le Tan Tim-Oliver Karstens Marina Creydt Stephan Seifert Thomas Hackl Markus Fischer |
| author_facet | Henri Loesel Navid Shakiba Soeren Wenck Phat Le Tan Tim-Oliver Karstens Marina Creydt Stephan Seifert Thomas Hackl Markus Fischer |
| author_sort | Henri Loesel |
| collection | DOAJ |
| description | Accelerated storage is routinely used with pharmaceuticals to predict stability and degradation patterns over time. The aim of this is to assess the shelf life and quality under harsher conditions, providing crucial insights into their long-term stability and potential storage issues. This study explores the potential of transferring this approach to food matrices for shelf-life estimation. Therefore, hazelnuts were stored under accelerated short-term and realistic long-term conditions. Subsequently, they were analyzed with high resolution mass spectrometry, focusing on the lipid profile. LC-MS analysis has shown that many unique processes take place under accelerated conditions that do not occur or occur much more slowly under realistic conditions. This mainly involved the degradation of membrane lipids such as phospholipids, ceramides, and digalactosyldiacylglycerides, while oxidation processes occurred at different rates in both conditions. It can be concluded that a food matrix is far too complex and heterogeneous compared to pharmaceuticals, so that many more processes take place during accelerated storage, which is why the results cannot be used to predict molecular changes in hazelnuts stored under realistic conditions. |
| first_indexed | 2024-03-10T21:03:41Z |
| format | Article |
| id | doaj.art-965ca6f1f5cd4441b2b43cc55fb1835a |
| institution | Directory Open Access Journal |
| issn | 2218-1989 |
| language | English |
| last_indexed | 2024-03-10T21:03:41Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Metabolites |
| spelling | doaj.art-965ca6f1f5cd4441b2b43cc55fb1835a2023-11-19T17:19:27ZengMDPI AGMetabolites2218-19892023-09-011310103110.3390/metabo13101031Food Monitoring: Limitations of Accelerated Storage to Predict Molecular Changes in Hazelnuts (<i>Corylus avellana</i> <span style="font-variant: small-caps">L</span>.) under Realistic Conditions Using UPLC-ESI-IM-QTOF-MSHenri Loesel0Navid Shakiba1Soeren Wenck2Phat Le Tan3Tim-Oliver Karstens4Marina Creydt5Stephan Seifert6Thomas Hackl7Markus Fischer8Hamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, GermanyAccelerated storage is routinely used with pharmaceuticals to predict stability and degradation patterns over time. The aim of this is to assess the shelf life and quality under harsher conditions, providing crucial insights into their long-term stability and potential storage issues. This study explores the potential of transferring this approach to food matrices for shelf-life estimation. Therefore, hazelnuts were stored under accelerated short-term and realistic long-term conditions. Subsequently, they were analyzed with high resolution mass spectrometry, focusing on the lipid profile. LC-MS analysis has shown that many unique processes take place under accelerated conditions that do not occur or occur much more slowly under realistic conditions. This mainly involved the degradation of membrane lipids such as phospholipids, ceramides, and digalactosyldiacylglycerides, while oxidation processes occurred at different rates in both conditions. It can be concluded that a food matrix is far too complex and heterogeneous compared to pharmaceuticals, so that many more processes take place during accelerated storage, which is why the results cannot be used to predict molecular changes in hazelnuts stored under realistic conditions.https://www.mdpi.com/2218-1989/13/10/1031hazelnutstorageion mobilitymass spectrometry<i>Corylus avellana</i>antioxidative capacity |
| spellingShingle | Henri Loesel Navid Shakiba Soeren Wenck Phat Le Tan Tim-Oliver Karstens Marina Creydt Stephan Seifert Thomas Hackl Markus Fischer Food Monitoring: Limitations of Accelerated Storage to Predict Molecular Changes in Hazelnuts (<i>Corylus avellana</i> <span style="font-variant: small-caps">L</span>.) under Realistic Conditions Using UPLC-ESI-IM-QTOF-MS Metabolites hazelnut storage ion mobility mass spectrometry <i>Corylus avellana</i> antioxidative capacity |
| title | Food Monitoring: Limitations of Accelerated Storage to Predict Molecular Changes in Hazelnuts (<i>Corylus avellana</i> <span style="font-variant: small-caps">L</span>.) under Realistic Conditions Using UPLC-ESI-IM-QTOF-MS |
| title_full | Food Monitoring: Limitations of Accelerated Storage to Predict Molecular Changes in Hazelnuts (<i>Corylus avellana</i> <span style="font-variant: small-caps">L</span>.) under Realistic Conditions Using UPLC-ESI-IM-QTOF-MS |
| title_fullStr | Food Monitoring: Limitations of Accelerated Storage to Predict Molecular Changes in Hazelnuts (<i>Corylus avellana</i> <span style="font-variant: small-caps">L</span>.) under Realistic Conditions Using UPLC-ESI-IM-QTOF-MS |
| title_full_unstemmed | Food Monitoring: Limitations of Accelerated Storage to Predict Molecular Changes in Hazelnuts (<i>Corylus avellana</i> <span style="font-variant: small-caps">L</span>.) under Realistic Conditions Using UPLC-ESI-IM-QTOF-MS |
| title_short | Food Monitoring: Limitations of Accelerated Storage to Predict Molecular Changes in Hazelnuts (<i>Corylus avellana</i> <span style="font-variant: small-caps">L</span>.) under Realistic Conditions Using UPLC-ESI-IM-QTOF-MS |
| title_sort | food monitoring limitations of accelerated storage to predict molecular changes in hazelnuts i corylus avellana i span style font variant small caps l span under realistic conditions using uplc esi im qtof ms |
| topic | hazelnut storage ion mobility mass spectrometry <i>Corylus avellana</i> antioxidative capacity |
| url | https://www.mdpi.com/2218-1989/13/10/1031 |
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