Receptor Interaction Profiles of 4-Alkoxy-Substituted 2,5-Dimethoxyphenethylamines and Related Amphetamines

Receptor Interaction Profiles of 4-Alkoxy-Substituted 2,5-Dimethoxyphenethylamines and Related Amphetamines

Background: 2,4,5-Trimethoxyamphetamine (TMA-2) is a potent psychedelic compound. Structurally related 4-alkyloxy-substituted 2,5-dimethoxyamphetamines and phenethylamine congeners (2C-O derivatives) have been described but their pharmacology is mostly undefined. Therefore, we examined receptor bind...

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Bibliographic Details
Main Authors: Karolina E. Kolaczynska, Dino Luethi, Daniel Trachsel, Marius C. Hoener, Matthias E. Liechti
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Pharmacology
Subjects:
2,4,5-trimethoxyamphetamine
phenethylamine
2C-O
3C-O
receptor
transporter
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01423/full

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