The Nuclear Translocation of Heme Oxygenase-1 in Human Diseases

The Nuclear Translocation of Heme Oxygenase-1 in Human Diseases

Heme oxygenase-1 (HO-1) is a rate-limiting enzyme in the degradation of heme to generate carbon monoxide (CO), free iron and biliverdin, which could then be converted to bilirubin by biliverdin reductase. HO-1 exhibits cytoprotective effects of anti-apoptosis, anti-oxidation, and anti-inflammation v...

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Bibliographic Details
Main Authors:	Qing Yang, Wenqian Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	heme oxygenase-1 nuclear translocation noncanonical function tumorigenesis inflammation anticancer therapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.890186/full

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