A STEREOLOGICAL UNFOLDING METHOD FOR THE STUDY OF THE MITOCHONDRIAL NETWORK
When the mitochondrial network within the cell is in a fragmented state, it resembles a spatial distribution of prolate spheroids of various shapes, sizes and orientations. This paper presents a maximum-likelihood scheme for inferring the distribution of spheroidal shapes, sizes and orientations fro...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Slovenian Society for Stereology and Quantitative Image Analysis
2011-05-01
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| Series: | Image Analysis and Stereology |
| Subjects: | |
| Online Access: | http://www.ias-iss.org/ojs/IAS/article/view/845 |
| Summary: | When the mitochondrial network within the cell is in a fragmented state, it resembles a spatial distribution of prolate spheroids of various shapes, sizes and orientations. This paper presents a maximum-likelihood scheme for inferring the distribution of spheroidal shapes, sizes and orientations from the observed distribution of elliptical sections. We also present a parametric bootstrap suitable for inferring confidence intervals for the parameters describing the shape and size distribution of the spheroids. |
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| ISSN: | 1580-3139 1854-5165 |