THE IMPORTANCE OF VIRAL DETECTION IN ORAL FLUIDS IN PATIENTS WITH PERIODONTAL DISEASE. REVIEW
The direct involvement of herpesviruses in the evolution of periodontitis can change the concepts of pathogenesis and disease management. A double periodontal infection of herpesviruses and pathogenic bacteria tends to be associated with more severe periodontitis than a periodontal infection involvi...
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| Format: | Article |
| Language: | English |
| Published: |
Romanian Dental Association for Education
2020-08-01
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| Series: | Romanian Journal of Medical and Dental Education |
| Subjects: | |
| Online Access: | http://www.journal.adre.ro/the-importance-of-viral-detection-in-oral-fluids-in-patients-with-periodontal-disease-review/ |
| _version_ | 1818281735182352384 |
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| author | Alexandru Flondor Irina-Georgeta Sufaru Maria-Alexandra Martu Ionut Luchian Liliana Pasarin Vasilica Toma Silvia Martu |
| author_facet | Alexandru Flondor Irina-Georgeta Sufaru Maria-Alexandra Martu Ionut Luchian Liliana Pasarin Vasilica Toma Silvia Martu |
| author_sort | Alexandru Flondor |
| collection | DOAJ |
| description | The direct involvement of herpesviruses in the evolution of periodontitis can change the concepts of pathogenesis and disease management. A double periodontal infection of herpesviruses and pathogenic bacteria tends to be associated with more severe periodontitis than a periodontal infection involving only bacteria. Classical techniques in viral diagnosis use cell culture or antigenemia. These diagnostic techniques have been largely replaced by DNA and / or RNA-based tests, which possess superior technical performance and cost advantages. False-negative and false-positive PCR results are an inherent concern. Poor design of the PCR test, without optimization or validation of the PCR methodology, may lead to inaccurate findings and incompatible with those of other studies. The concept of viral infections of the diseased periodontium may introduce a new level of understanding of the importance of preventing and controlling periodontal disease for medical purposes |
| first_indexed | 2024-12-13T00:09:50Z |
| format | Article |
| id | doaj.art-9667a87e27fa417484c94e6ef2fcc821 |
| institution | Directory Open Access Journal |
| issn | 2393-1108 2393-1531 |
| language | English |
| last_indexed | 2024-12-13T00:09:50Z |
| publishDate | 2020-08-01 |
| publisher | Romanian Dental Association for Education |
| record_format | Article |
| series | Romanian Journal of Medical and Dental Education |
| spelling | doaj.art-9667a87e27fa417484c94e6ef2fcc8212022-12-22T00:06:01ZengRomanian Dental Association for EducationRomanian Journal of Medical and Dental Education2393-11082393-15312020-08-01945968THE IMPORTANCE OF VIRAL DETECTION IN ORAL FLUIDS IN PATIENTS WITH PERIODONTAL DISEASE. REVIEWAlexandru Flondor0Irina-Georgeta Sufaru1Maria-Alexandra Martu2Ionut Luchian3Liliana Pasarin4Vasilica Toma5Silvia Martu6DMD, PhD, Private Practice, Iasi, RomaniUniversity of Medicine and Pharmacy “Grigore T. Popa”, Faculty of Dental Medicine, Department of Periodontology, Iasi, RomaniaUniversity of Medicine and Pharmacy “Grigore T. Popa”, Faculty of Dental Medicine, Department of Periodontology, Iasi, RomaniaUniversity of Medicine and Pharmacy “Grigore T. Popa”, Faculty of Dental Medicine, Department of Periodontology, Iasi, RomaniaUniversity of Medicine and Pharmacy “Grigore T. Popa”, Faculty of Dental Medicine, Department of Periodontology, Iasi, RomaniaUniversity of Medicine and Pharmacy “Grigore T. Popa”, Faculty of Dental Medicine, Department of Pediatric Dentistry, Iasi, Romania University of Medicine and Pharmacy “Grigore T. Popa”, Faculty of Dental Medicine, Department of Periodontology, Iasi, RomaniaThe direct involvement of herpesviruses in the evolution of periodontitis can change the concepts of pathogenesis and disease management. A double periodontal infection of herpesviruses and pathogenic bacteria tends to be associated with more severe periodontitis than a periodontal infection involving only bacteria. Classical techniques in viral diagnosis use cell culture or antigenemia. These diagnostic techniques have been largely replaced by DNA and / or RNA-based tests, which possess superior technical performance and cost advantages. False-negative and false-positive PCR results are an inherent concern. Poor design of the PCR test, without optimization or validation of the PCR methodology, may lead to inaccurate findings and incompatible with those of other studies. The concept of viral infections of the diseased periodontium may introduce a new level of understanding of the importance of preventing and controlling periodontal disease for medical purposeshttp://www.journal.adre.ro/the-importance-of-viral-detection-in-oral-fluids-in-patients-with-periodontal-disease-review/virusesperiodontal bacteriasalivacrevicular fluidpcr |
| spellingShingle | Alexandru Flondor Irina-Georgeta Sufaru Maria-Alexandra Martu Ionut Luchian Liliana Pasarin Vasilica Toma Silvia Martu THE IMPORTANCE OF VIRAL DETECTION IN ORAL FLUIDS IN PATIENTS WITH PERIODONTAL DISEASE. REVIEW Romanian Journal of Medical and Dental Education viruses periodontal bacteria saliva crevicular fluid pcr |
| title | THE IMPORTANCE OF VIRAL DETECTION IN ORAL FLUIDS IN PATIENTS WITH PERIODONTAL DISEASE. REVIEW |
| title_full | THE IMPORTANCE OF VIRAL DETECTION IN ORAL FLUIDS IN PATIENTS WITH PERIODONTAL DISEASE. REVIEW |
| title_fullStr | THE IMPORTANCE OF VIRAL DETECTION IN ORAL FLUIDS IN PATIENTS WITH PERIODONTAL DISEASE. REVIEW |
| title_full_unstemmed | THE IMPORTANCE OF VIRAL DETECTION IN ORAL FLUIDS IN PATIENTS WITH PERIODONTAL DISEASE. REVIEW |
| title_short | THE IMPORTANCE OF VIRAL DETECTION IN ORAL FLUIDS IN PATIENTS WITH PERIODONTAL DISEASE. REVIEW |
| title_sort | importance of viral detection in oral fluids in patients with periodontal disease review |
| topic | viruses periodontal bacteria saliva crevicular fluid pcr |
| url | http://www.journal.adre.ro/the-importance-of-viral-detection-in-oral-fluids-in-patients-with-periodontal-disease-review/ |
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