Adaptation of the intact proviral DNA assay to a nanowell-based digital PCR platform

Adaptation of the intact proviral DNA assay to a nanowell-based digital PCR platform

Quantification of intact proviruses is a critical measurement in HIV cure studies both in vitro and in vivo. The widely adopted ‘intact proviral DNA assay’ (IPDA), designed to discriminate and quantify genetically intact HIV proviruses based on detection of two HIV sequence-specific targets, was ori...

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Bibliographic Details
Main Authors: Carolin Tumpach, Catherine R. Cochrane, Youry Kim, Jesslyn Ong, Ajantha Rhodes, Thomas A. Angelovich, Melissa J. Churchill, Sharon R. Lewin, Sushama Telwatte, Michael Roche
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Journal of Virus Eradication
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664023000213

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