Lack of association between six-minute walk distance and pulmonary artery pressure in patients with systemic sclerosis and cardiopulmonary symptoms
The six-minute walk test (6MWT) is a non-invasive test used to assess cardiopulmonary performance. The aim of this study was to evaluate the performance of 6MWT in predicting pulmonary artery hypertension (PAH) and interstitial lung disease in patients with systemic sclerosis (SSc) and cardiopulmona...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2020-09-01
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| Series: | Journal of Cardiovascular and Thoracic Research |
| Subjects: | |
| Online Access: | https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-12-244.pdf |
| _version_ | 1818927817008611328 |
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| author | Leila Namvar Alireza Khabbazi Sabbah Hasani Masoud Nazemiyeh |
| author_facet | Leila Namvar Alireza Khabbazi Sabbah Hasani Masoud Nazemiyeh |
| author_sort | Leila Namvar |
| collection | DOAJ |
| description | The six-minute walk test (6MWT) is a non-invasive test used to assess cardiopulmonary performance. The aim of this study was to evaluate the performance of 6MWT in predicting pulmonary artery hypertension (PAH) and interstitial lung disease in patients with systemic sclerosis (SSc) and cardiopulmonary symptoms. Sixty-three patients with SSc who had dyspnea, cough, chest pain and syncope underwent 6MWT, high-resolution computed tomography (HRCT), spirometry, body plethysmography and single breath carbon monoxide diffusion measurement. There were no significant differences in mean 6MWD between patients with diffuse SSc compared with limited disease, patients with no parenchymal involvement compared with patients with parenchymal involvement <20% and≥20% in HRCT, and patients with PAP ≥25 mm Hg compared with patents with PAP <25 mm Hg. No significant relationship was found between 6MWD and age, mean PAP, forced expiratory volume, forced vital capacity and diffusing capacity of the lungs for carbon monoxide. The present study showed that in patients with SSc and cardiopulmonary symptoms, 6MVT does not help to predict PAH and parenchymal lung involvement. |
| first_indexed | 2024-12-20T03:19:02Z |
| format | Article |
| id | doaj.art-96691b01136f45f1a90401b49416d58e |
| institution | Directory Open Access Journal |
| issn | 2008-5117 2008-6830 |
| language | English |
| last_indexed | 2024-12-20T03:19:02Z |
| publishDate | 2020-09-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Cardiovascular and Thoracic Research |
| spelling | doaj.art-96691b01136f45f1a90401b49416d58e2022-12-21T19:55:16ZengTabriz University of Medical SciencesJournal of Cardiovascular and Thoracic Research2008-51172008-68302020-09-0112324424510.34172/jcvtr.2020.42jcvtr-28696Lack of association between six-minute walk distance and pulmonary artery pressure in patients with systemic sclerosis and cardiopulmonary symptomsLeila Namvar0Alireza Khabbazi1Sabbah Hasani2Masoud Nazemiyeh3Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, IranConnective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, IranTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, IranTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, IranThe six-minute walk test (6MWT) is a non-invasive test used to assess cardiopulmonary performance. The aim of this study was to evaluate the performance of 6MWT in predicting pulmonary artery hypertension (PAH) and interstitial lung disease in patients with systemic sclerosis (SSc) and cardiopulmonary symptoms. Sixty-three patients with SSc who had dyspnea, cough, chest pain and syncope underwent 6MWT, high-resolution computed tomography (HRCT), spirometry, body plethysmography and single breath carbon monoxide diffusion measurement. There were no significant differences in mean 6MWD between patients with diffuse SSc compared with limited disease, patients with no parenchymal involvement compared with patients with parenchymal involvement <20% and≥20% in HRCT, and patients with PAP ≥25 mm Hg compared with patents with PAP <25 mm Hg. No significant relationship was found between 6MWD and age, mean PAP, forced expiratory volume, forced vital capacity and diffusing capacity of the lungs for carbon monoxide. The present study showed that in patients with SSc and cardiopulmonary symptoms, 6MVT does not help to predict PAH and parenchymal lung involvement.https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-12-244.pdfsystemic sclerosissix-minute walk testsix-minute walk distancepulmonary pressurepulmonary hypertension |
| spellingShingle | Leila Namvar Alireza Khabbazi Sabbah Hasani Masoud Nazemiyeh Lack of association between six-minute walk distance and pulmonary artery pressure in patients with systemic sclerosis and cardiopulmonary symptoms Journal of Cardiovascular and Thoracic Research systemic sclerosis six-minute walk test six-minute walk distance pulmonary pressure pulmonary hypertension |
| title | Lack of association between six-minute walk distance and pulmonary artery pressure in patients with systemic sclerosis and cardiopulmonary symptoms |
| title_full | Lack of association between six-minute walk distance and pulmonary artery pressure in patients with systemic sclerosis and cardiopulmonary symptoms |
| title_fullStr | Lack of association between six-minute walk distance and pulmonary artery pressure in patients with systemic sclerosis and cardiopulmonary symptoms |
| title_full_unstemmed | Lack of association between six-minute walk distance and pulmonary artery pressure in patients with systemic sclerosis and cardiopulmonary symptoms |
| title_short | Lack of association between six-minute walk distance and pulmonary artery pressure in patients with systemic sclerosis and cardiopulmonary symptoms |
| title_sort | lack of association between six minute walk distance and pulmonary artery pressure in patients with systemic sclerosis and cardiopulmonary symptoms |
| topic | systemic sclerosis six-minute walk test six-minute walk distance pulmonary pressure pulmonary hypertension |
| url | https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-12-244.pdf |
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