Comparison of CECT and CT perfusion in differentiating benign from malignant neck nodes in oral cavity cancers
Aim: The objective of the study was to assess the performance of CT Perfusion in comparison to CECT for preoperative detection of metastases to lymph nodes in squamous cell cancers of oral cavity. Methods: Twenty-five patients with squamous cell cancers of oral cavity underwent CECT and CTP. Two rad...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-01-01
|
| Series: | European Journal of Radiology Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352047721000198 |
| _version_ | 1819095329872543744 |
|---|---|
| author | Shubham Suryavanshi Jyoti Kumar Alpana Manchanda Ishwar Singh Nita Khurana |
| author_facet | Shubham Suryavanshi Jyoti Kumar Alpana Manchanda Ishwar Singh Nita Khurana |
| author_sort | Shubham Suryavanshi |
| collection | DOAJ |
| description | Aim: The objective of the study was to assess the performance of CT Perfusion in comparison to CECT for preoperative detection of metastases to lymph nodes in squamous cell cancers of oral cavity. Methods: Twenty-five patients with squamous cell cancers of oral cavity underwent CECT and CTP. Two radiologists evaluated CECT and CTP parameters independently. Surgery and post-operative histopathology was performed in all patients. Results: Level wise analysis of the largest node was done. 102 lymph nodes on CECT and 82 lymph nodes on CTP were correlated with post-operative histopathological findings. CECT had a sensitivity, specificity and accuracy of 75 %, 98.6 % and 91.2 %(p-value <0.001) respectively in differentiating benign from metastatic nodes. Mean transit time[MTT] was significantly the most accurate CTP parameter and carried a sensitivity, specificity, accuracy and AUC of 90.5 %, 93.4 %, 92.7 % and 0.96 (p < 0.001). The sensitivity of MTT was higher than the sensitivity of overall CECT. Conclusions: CTP is a promising tool for detection of metastatic cervical nodes in squamous cell cancers of the oral cavity. |
| first_indexed | 2024-12-21T23:41:35Z |
| format | Article |
| id | doaj.art-966cfa9c269b47a38e343b2357a911b9 |
| institution | Directory Open Access Journal |
| issn | 2352-0477 |
| language | English |
| last_indexed | 2024-12-21T23:41:35Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | European Journal of Radiology Open |
| spelling | doaj.art-966cfa9c269b47a38e343b2357a911b92022-12-21T18:46:13ZengElsevierEuropean Journal of Radiology Open2352-04772021-01-018100339Comparison of CECT and CT perfusion in differentiating benign from malignant neck nodes in oral cavity cancersShubham Suryavanshi0Jyoti Kumar1Alpana Manchanda2Ishwar Singh3Nita Khurana4Department of Radiodiagnosis, Maulana Azad Medical College & Associated Hospitals, New Delhi, Delhi, IndiaDepartment of Radiodiagnosis, Maulana Azad Medical College & Associated Hospitals, New Delhi, Delhi, India; Corresponding author at: Maulana Azad Medical College & Associated Hospitals, Bahadurshah Zafar Marg, 110002, New Delhi-Central, Delhi, India.Department of Radiodiagnosis, Maulana Azad Medical College & Associated Hospitals, New Delhi, Delhi, IndiaDepartment of Otorhinolaryngology Head and Neck Surgery, Maulana Azad Medical College & Associated Hospitals, New Delhi, Delhi, IndiaDepartment of Pathology, Maulana Azad Medical College & Associated Hospitals, New Delhi, Delhi, IndiaAim: The objective of the study was to assess the performance of CT Perfusion in comparison to CECT for preoperative detection of metastases to lymph nodes in squamous cell cancers of oral cavity. Methods: Twenty-five patients with squamous cell cancers of oral cavity underwent CECT and CTP. Two radiologists evaluated CECT and CTP parameters independently. Surgery and post-operative histopathology was performed in all patients. Results: Level wise analysis of the largest node was done. 102 lymph nodes on CECT and 82 lymph nodes on CTP were correlated with post-operative histopathological findings. CECT had a sensitivity, specificity and accuracy of 75 %, 98.6 % and 91.2 %(p-value <0.001) respectively in differentiating benign from metastatic nodes. Mean transit time[MTT] was significantly the most accurate CTP parameter and carried a sensitivity, specificity, accuracy and AUC of 90.5 %, 93.4 %, 92.7 % and 0.96 (p < 0.001). The sensitivity of MTT was higher than the sensitivity of overall CECT. Conclusions: CTP is a promising tool for detection of metastatic cervical nodes in squamous cell cancers of the oral cavity.http://www.sciencedirect.com/science/article/pii/S2352047721000198CT perfusionCECTSquamous cell cancerLymph nodes |
| spellingShingle | Shubham Suryavanshi Jyoti Kumar Alpana Manchanda Ishwar Singh Nita Khurana Comparison of CECT and CT perfusion in differentiating benign from malignant neck nodes in oral cavity cancers European Journal of Radiology Open CT perfusion CECT Squamous cell cancer Lymph nodes |
| title | Comparison of CECT and CT perfusion in differentiating benign from malignant neck nodes in oral cavity cancers |
| title_full | Comparison of CECT and CT perfusion in differentiating benign from malignant neck nodes in oral cavity cancers |
| title_fullStr | Comparison of CECT and CT perfusion in differentiating benign from malignant neck nodes in oral cavity cancers |
| title_full_unstemmed | Comparison of CECT and CT perfusion in differentiating benign from malignant neck nodes in oral cavity cancers |
| title_short | Comparison of CECT and CT perfusion in differentiating benign from malignant neck nodes in oral cavity cancers |
| title_sort | comparison of cect and ct perfusion in differentiating benign from malignant neck nodes in oral cavity cancers |
| topic | CT perfusion CECT Squamous cell cancer Lymph nodes |
| url | http://www.sciencedirect.com/science/article/pii/S2352047721000198 |
| work_keys_str_mv | AT shubhamsuryavanshi comparisonofcectandctperfusionindifferentiatingbenignfrommalignantnecknodesinoralcavitycancers AT jyotikumar comparisonofcectandctperfusionindifferentiatingbenignfrommalignantnecknodesinoralcavitycancers AT alpanamanchanda comparisonofcectandctperfusionindifferentiatingbenignfrommalignantnecknodesinoralcavitycancers AT ishwarsingh comparisonofcectandctperfusionindifferentiatingbenignfrommalignantnecknodesinoralcavitycancers AT nitakhurana comparisonofcectandctperfusionindifferentiatingbenignfrommalignantnecknodesinoralcavitycancers |