High risk oral contraceptive hormones do not directly enhance endothelial cell procoagulant activity in vitro

<h4>Background</h4> Oral contraceptive (OC) use increases venous thromboembolism risk 2-5-fold. Procoagulant changes can be detected in plasma from OC users even without thrombosis, but cellular mechanisms that provoke thrombosis have not been identified. Endothelial cell (EC) dysfunctio...

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Bibliographic Details
Main Authors: Emma G. Bouck, Marios Arvanitis, William O. Osburn, Yaqiu Sang, Paula Reventun, Homa K. Ahmadzia, Nicholas L. Smith, Charles J. Lowenstein, Alisa S. Wolberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115293/?tool=EBI