Prevalence, types, clinical associations, and determinants of peripheral neuropathy in rheumatoid patients
Background: Rheumatoid arthritis is a multi-system autoimmune disorder predominantly involving multiple small and large joints along with certain extra-articular manifestations. The presence of peripheral neuropathy in patients with rheumatoid arthritis contributes significantly to the functional li...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2011-01-01
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| Series: | Annals of Indian Academy of Neurology |
| Subjects: | |
| Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=3;spage=194;epage=197;aulast=Biswas |
| _version_ | 1819267722403381248 |
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| author | Monodeep Biswas Arghya Chatterjee Sudip Kumar Ghosh S Dasgupta Kartik Ghosh P K Ganguly |
| author_facet | Monodeep Biswas Arghya Chatterjee Sudip Kumar Ghosh S Dasgupta Kartik Ghosh P K Ganguly |
| author_sort | Monodeep Biswas |
| collection | DOAJ |
| description | Background: Rheumatoid arthritis is a multi-system autoimmune disorder predominantly involving multiple small and large joints along with certain extra-articular manifestations. The presence of peripheral neuropathy in patients with rheumatoid arthritis contributes significantly to the functional limitation in patients with rheumatoid arthritis. Objectives: To study the prevalence, types, and determinants of peripheral neuropathy in patients with rheumatoid arthritis. Materials and Methods: We studied 74 patients with rheumatoid arthritis of at least 2 year duration for the presence of peripheral neuropathy both clinically and electrophysiologically. The data obtained were entered into a database and continuous variables were analyzed using the Student t test and categorical variables were analyzed using the chi-square test. Results: Peripheral neuropathy was detected in 39.19% (29 out of 74 patients) patients on electrophysiologic testing and 82.76% (24 out of 29 patients) of the patients were asymptomatic. There was significant association between the presence of peripheral neuropathy and disease duration and rheumatoid factor positivity by the latex agglutination method. Sensory neuropathy was the most common form detected. Conclusions: Our study shows that subclinical peripheral neuropathy particularly sensory neuropathy which is not related to disease severity is very common in patients with prolonged disease duration. |
| first_indexed | 2024-12-23T21:21:41Z |
| format | Article |
| id | doaj.art-967356b6a70c4b65b65d276b8a41b687 |
| institution | Directory Open Access Journal |
| issn | 0972-2327 1998-3549 |
| language | English |
| last_indexed | 2024-12-23T21:21:41Z |
| publishDate | 2011-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Academy of Neurology |
| spelling | doaj.art-967356b6a70c4b65b65d276b8a41b6872022-12-21T17:30:43ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492011-01-0114319419710.4103/0972-2327.85893Prevalence, types, clinical associations, and determinants of peripheral neuropathy in rheumatoid patientsMonodeep BiswasArghya ChatterjeeSudip Kumar GhoshS DasguptaKartik GhoshP K GangulyBackground: Rheumatoid arthritis is a multi-system autoimmune disorder predominantly involving multiple small and large joints along with certain extra-articular manifestations. The presence of peripheral neuropathy in patients with rheumatoid arthritis contributes significantly to the functional limitation in patients with rheumatoid arthritis. Objectives: To study the prevalence, types, and determinants of peripheral neuropathy in patients with rheumatoid arthritis. Materials and Methods: We studied 74 patients with rheumatoid arthritis of at least 2 year duration for the presence of peripheral neuropathy both clinically and electrophysiologically. The data obtained were entered into a database and continuous variables were analyzed using the Student t test and categorical variables were analyzed using the chi-square test. Results: Peripheral neuropathy was detected in 39.19% (29 out of 74 patients) patients on electrophysiologic testing and 82.76% (24 out of 29 patients) of the patients were asymptomatic. There was significant association between the presence of peripheral neuropathy and disease duration and rheumatoid factor positivity by the latex agglutination method. Sensory neuropathy was the most common form detected. Conclusions: Our study shows that subclinical peripheral neuropathy particularly sensory neuropathy which is not related to disease severity is very common in patients with prolonged disease duration.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=3;spage=194;epage=197;aulast=BiswasMononeuritisneuropathyperipheralrheumatoidsensorysensorimotor |
| spellingShingle | Monodeep Biswas Arghya Chatterjee Sudip Kumar Ghosh S Dasgupta Kartik Ghosh P K Ganguly Prevalence, types, clinical associations, and determinants of peripheral neuropathy in rheumatoid patients Annals of Indian Academy of Neurology Mononeuritis neuropathy peripheral rheumatoid sensory sensorimotor |
| title | Prevalence, types, clinical associations, and determinants of peripheral neuropathy in rheumatoid patients |
| title_full | Prevalence, types, clinical associations, and determinants of peripheral neuropathy in rheumatoid patients |
| title_fullStr | Prevalence, types, clinical associations, and determinants of peripheral neuropathy in rheumatoid patients |
| title_full_unstemmed | Prevalence, types, clinical associations, and determinants of peripheral neuropathy in rheumatoid patients |
| title_short | Prevalence, types, clinical associations, and determinants of peripheral neuropathy in rheumatoid patients |
| title_sort | prevalence types clinical associations and determinants of peripheral neuropathy in rheumatoid patients |
| topic | Mononeuritis neuropathy peripheral rheumatoid sensory sensorimotor |
| url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=3;spage=194;epage=197;aulast=Biswas |
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