Flavokawain A Reduces Tumor-Initiating Properties and Stemness of Prostate Cancer

Flavokawain A Reduces Tumor-Initiating Properties and Stemness of Prostate Cancer

We have previously demonstrated the in vivo chemopreventive efficacy of flavokawain A (FKA), a novel chalcone from the kava plant, in prostate carcinogenesis models. However, the mechanisms of the anticarcinogenic effects of FKA remain largely unknown. We evaluated the effect of FKA on prostate tumo...

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Bibliographic Details
Main Authors: Liankun Song, Merci Mino, Jana Yamak, Vyvyan Nguyen, Derron Lopez, Victor Pham, Ali Fazelpour, Vinh Le, Dongjun Fu, Matthew Tippin, Edward Uchio, Xiaolin Zi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
Flavokawain A
Chemoprevention
prostate cancer
cancer stem cells
Neddylation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.943846/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.943846/full

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