Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report
Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and bios...
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MDPI AG
2020-10-01
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Series: | Sensors |
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Online Access: | https://www.mdpi.com/1424-8220/20/19/5639 |
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author | Arshak Poghossian Michael J. Schöning |
author_facet | Arshak Poghossian Michael J. Schöning |
author_sort | Arshak Poghossian |
collection | DOAJ |
description | Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed. |
first_indexed | 2024-03-10T15:53:05Z |
format | Article |
id | doaj.art-967d71e914f04d58985dfdaaefb0e8ae |
institution | Directory Open Access Journal |
issn | 1424-8220 |
language | English |
last_indexed | 2024-03-10T15:53:05Z |
publishDate | 2020-10-01 |
publisher | MDPI AG |
record_format | Article |
series | Sensors |
spelling | doaj.art-967d71e914f04d58985dfdaaefb0e8ae2023-11-20T15:53:42ZengMDPI AGSensors1424-82202020-10-012019563910.3390/s20195639Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status ReportArshak Poghossian0Michael J. Schöning1MicroNanoBio, Liebigstr. 4, 40479 Düsseldorf, GermanyInstitute of Nano- and Biotechnologies (INB), FH Aachen, Campus Jülich, Heinrich-Mußmannstr. 1, 52428 Jülich, GermanyElectrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed.https://www.mdpi.com/1424-8220/20/19/5639chemical sensorbiosensorfield effectcapacitive EIS sensorpH sensorenzyme biosensor |
spellingShingle | Arshak Poghossian Michael J. Schöning Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report Sensors chemical sensor biosensor field effect capacitive EIS sensor pH sensor enzyme biosensor |
title | Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report |
title_full | Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report |
title_fullStr | Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report |
title_full_unstemmed | Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report |
title_short | Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report |
title_sort | capacitive field effect eis chemical sensors and biosensors a status report |
topic | chemical sensor biosensor field effect capacitive EIS sensor pH sensor enzyme biosensor |
url | https://www.mdpi.com/1424-8220/20/19/5639 |
work_keys_str_mv | AT arshakpoghossian capacitivefieldeffecteischemicalsensorsandbiosensorsastatusreport AT michaeljschoning capacitivefieldeffecteischemicalsensorsandbiosensorsastatusreport |