Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report

Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and bios...

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Main Authors: Arshak Poghossian, Michael J. Schöning
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/20/19/5639
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author Arshak Poghossian
Michael J. Schöning
author_facet Arshak Poghossian
Michael J. Schöning
author_sort Arshak Poghossian
collection DOAJ
description Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed.
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spelling doaj.art-967d71e914f04d58985dfdaaefb0e8ae2023-11-20T15:53:42ZengMDPI AGSensors1424-82202020-10-012019563910.3390/s20195639Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status ReportArshak Poghossian0Michael J. Schöning1MicroNanoBio, Liebigstr. 4, 40479 Düsseldorf, GermanyInstitute of Nano- and Biotechnologies (INB), FH Aachen, Campus Jülich, Heinrich-Mußmannstr. 1, 52428 Jülich, GermanyElectrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed.https://www.mdpi.com/1424-8220/20/19/5639chemical sensorbiosensorfield effectcapacitive EIS sensorpH sensorenzyme biosensor
spellingShingle Arshak Poghossian
Michael J. Schöning
Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report
Sensors
chemical sensor
biosensor
field effect
capacitive EIS sensor
pH sensor
enzyme biosensor
title Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report
title_full Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report
title_fullStr Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report
title_full_unstemmed Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report
title_short Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report
title_sort capacitive field effect eis chemical sensors and biosensors a status report
topic chemical sensor
biosensor
field effect
capacitive EIS sensor
pH sensor
enzyme biosensor
url https://www.mdpi.com/1424-8220/20/19/5639
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