Substitution of the CD81 Binding Site and β-Sandwich Area in E2 of HCV in Cambodia

Substitution of the CD81 Binding Site and β-Sandwich Area in E2 of HCV in Cambodia

The high genetic variability of hepatitis C virus (HCV) is the main obstacle to developing a vaccine. E2 has attracted attention for vaccine development because targeting this protein could potentially overcome issues related to the genetic diversity of HCV. In this study, we analyzed HCV genes in t...

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Bibliographic Details
Main Authors: Chikako Yamamoto, Shintaro Nagashima, Channarena Chuon, Ko Ko, Son Huy Do, Oline Lim, Sirany Hok, Somana Svay, Junko Matsuo, Keiko Katayama, Kazuaki Takahashi, Junko Tanaka
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Viruses
Subjects:
hepatitis C virus
Cambodia
general population
mutation rate
CD81 binding site
Online Access:https://www.mdpi.com/1999-4915/12/5/551

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https://www.mdpi.com/1999-4915/12/5/551

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