Transient Congenital Hypothyroidism Alters Gene Expression of Glucose Transporters and Impairs Glucose Sensing Apparatus in Young and Aged Offspring Rats

Transient Congenital Hypothyroidism Alters Gene Expression of Glucose Transporters and Impairs Glucose Sensing Apparatus in Young and Aged Offspring Rats

Background/Aims: Transient congenital hypothyroidism (TCH) could disturb carbohydrate metabolism in adulthood. Aging is associated with increased risk of type 2 diabetes. This study aims to address effects of TCH on mRNA expressions of glucose transporters (GLUTs) and glucokinase (GcK) in islets and...

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Bibliographic Details
Main Authors: Hanieh Gholami, Sajad Jeddi, Azita Zadeh-Vakili, Khadije Farrokhfall, Fatemeh Rouhollah, Maryam Zarkesh, Mahboubeh Ghanbari, Asghar Ghasemi
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Transient congenital hypothyroidism
Carbohydrate metabolism
Insulin
Rat
Glucose transporter
Online Access:https://www.karger.com/Article/FullText/484386

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