Toxicity of azathioprine: why and when? analysis of the prevalence of polymorphism in Joinville, SC, Brazil

Toxicity of azathioprine: why and when? analysis of the prevalence of polymorphism in Joinville, SC, Brazil

CONTEXT: The use of thiopurine drugs such as azathioprine and 6-mercaptopurine has become quite common in the treatment of inflammatory bowel disease, transplantation and acute leukemias. Despite their effectiveness, these drugs are capable of causing drug-induced toxicity with the risk of death by...

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Bibliographic Details
Main Authors: Gabriela Roncone Gastal, Simone Moreira, Caroline Furtado Noble, Leslie Ecker Ferreira, Paulo Henrique Condeixa de França, Mauro Pinho
Format: Article
Language:English
Published: Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) 2012-06-01
Series:Arquivos de Gastroenterologia
Subjects:
Azatioprina
toxicidade
6-mercaptopurina
Doenças inflamatórias intestinais
Polimorfismo genético
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032012000200007&lng=en&tlng=en

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