FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION
Various parameters of neutrophil reactivity, i.e., superoxide anion-forming ability (NВT-test), formation of the extracellular networks (NET) and phagocytic function, were studied in sixty-six patients with severe form of chronic recurrent herpetic infection. In resting leukocyte cultures from the p...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/129 |
| _version_ | 1797198173949657088 |
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| author | N. V. Gusakova I. A. Novikova |
| author_facet | N. V. Gusakova I. A. Novikova |
| author_sort | N. V. Gusakova |
| collection | DOAJ |
| description | Various parameters of neutrophil reactivity, i.e., superoxide anion-forming ability (NВT-test), formation of the extracellular networks (NET) and phagocytic function, were studied in sixty-six patients with severe form of chronic recurrent herpetic infection. In resting leukocyte cultures from the patients, regardless of the disease stage, NВT scores were higher, and NET values were lower, than in control group. In stimulated cultures, NВT response was decreased, whereas NET parameters were higher than reference values. The changes in NET, but not NВT scores, were more pronounced in patients during the disease exacerbtion and in combined form of herpesvirus infection. |
| first_indexed | 2024-03-08T05:51:48Z |
| format | Article |
| id | doaj.art-96842aa55a1a4833b22a383785b669e1 |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2024-04-24T06:55:39Z |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-96842aa55a1a4833b22a383785b669e12024-04-22T13:07:33ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0115216917610.15789/1563-0625-2013-2-169-176126FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTIONN. V. Gusakova0I. A. Novikova1Gomel State Medical University, GomelGomel State Medical University, GomelVarious parameters of neutrophil reactivity, i.e., superoxide anion-forming ability (NВT-test), formation of the extracellular networks (NET) and phagocytic function, were studied in sixty-six patients with severe form of chronic recurrent herpetic infection. In resting leukocyte cultures from the patients, regardless of the disease stage, NВT scores were higher, and NET values were lower, than in control group. In stimulated cultures, NВT response was decreased, whereas NET parameters were higher than reference values. The changes in NET, but not NВT scores, were more pronounced in patients during the disease exacerbtion and in combined form of herpesvirus infection.https://www.mimmun.ru/mimmun/article/view/129herpes infectionfunctional activity of neutrophils |
| spellingShingle | N. V. Gusakova I. A. Novikova FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION Медицинская иммунология herpes infection functional activity of neutrophils |
| title | FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
| title_full | FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
| title_fullStr | FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
| title_full_unstemmed | FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
| title_short | FUNCTIONAL ACTIVITIES OF NEUTROPHILS IN CHRONIC RECURRENT HERPETIC INFECTION |
| title_sort | functional activities of neutrophils in chronic recurrent herpetic infection |
| topic | herpes infection functional activity of neutrophils |
| url | https://www.mimmun.ru/mimmun/article/view/129 |
| work_keys_str_mv | AT nvgusakova functionalactivitiesofneutrophilsinchronicrecurrentherpeticinfection AT ianovikova functionalactivitiesofneutrophilsinchronicrecurrentherpeticinfection |