The endothelin system in breast tumour - endothelial cell interactions
The role of endothelin-1 (ET-1) and its receptors (ET-RA and ET-RB) in tumour development and progression involves complex interactions. ET-1, produced by tumours and associated cells like endothelial cells, functions in an autocrine and paracrine manner to promote tumour angiogenesis. Thus, we h...
Main Authors: | Tasnim Badat, Julia Botha, Strinivasen Naidoo |
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Format: | Article |
Language: | English |
Published: |
Academy of Science of South Africa
2011-01-01
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Series: | South African Journal of Science |
Subjects: | |
Online Access: | https://www.sajs.co.za/article/view/10079 |
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