Patterns of glomerular disease based on 4-year kidney biopsy material analyzed by light microscopy and immunofluorescence: a retrospective single-center analysis in Poland
The aim of this study was to assess the epidemiology of different patterns of chronic glomerular diseases based on clinical, histopathological and immunofluorescent findings of glomerulonephritis patients hospitalized in the Department of Nephrology, Transplantology and Internal Diseases in Poznan b...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2017-02-01
|
| Series: | Polish Journal of Pathology |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Patterns-of-glomerular-disease-based-on-4-year-kidney-biopsy-material-analyzed-by-light-microscopy-and-immunofluorescence-a-retrospective-single-center-analysis-in-Poland,55,29479,1,1.html |
| _version_ | 1818498868053016576 |
|---|---|
| author | Anna Olewicz-Gawlik Dorota Sikorska Agnieszka Pluto-Prądzyńska Magdalena Roszak Ilona Idasiak-Piechocka Krzysztof Pawlaczyk Andrzej Oko Aldona Woźniak Katarzyna Iwanik Grzegorz Dworacki Jan Sikora Jan Żeromski |
| author_facet | Anna Olewicz-Gawlik Dorota Sikorska Agnieszka Pluto-Prądzyńska Magdalena Roszak Ilona Idasiak-Piechocka Krzysztof Pawlaczyk Andrzej Oko Aldona Woźniak Katarzyna Iwanik Grzegorz Dworacki Jan Sikora Jan Żeromski |
| author_sort | Anna Olewicz-Gawlik |
| collection | DOAJ |
| description | The aim of this study was to assess the epidemiology of different patterns of chronic glomerular diseases based on clinical, histopathological and immunofluorescent findings of glomerulonephritis patients hospitalized in the Department of Nephrology, Transplantology and Internal Diseases in Poznan between January 2009 and December 2012.
We retrospectively studied 418 patients who had been subjected to renal biopsies. Data on serum creatinine concentration, 24 h proteinuria, arterial hypertension, diabetes mellitus, and histological and immunofluorescent findings were collected.
The patients’ mean age was 42 ±15. The male sex prevailed (53.1%). Immunoglobulin A nephropathy was the most common finding (18.9%), followed by focal segmental glomerulosclerosis (16.3%), membranous glomerulonephritis (10.1%), lupus nephritis (8.4%), extracapillary glomerulonephritis (3.3%) and membranoproliferative glomerulonephritis (2.6%). In 69 (16.5%) patients the biopsy was non-informative or non-diagnostic. Patients with membranous nephropathy presented the highest frequency of nephrotic syndrome (71.4%), followed by membranoproliferative glomerulonephritis and focal segmental glomerulosclerosis.
Combined analysis of the clinical, histopathological and immunofluorescent findings in glomerulonephritis patients based on a single center’s data can provide important epidemiological findings. |
| first_indexed | 2024-12-10T20:21:26Z |
| format | Article |
| id | doaj.art-96869b9c8eea4cdaa6df33ca4e214824 |
| institution | Directory Open Access Journal |
| issn | 1233-9687 2084-9869 |
| language | English |
| last_indexed | 2024-12-10T20:21:26Z |
| publishDate | 2017-02-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Polish Journal of Pathology |
| spelling | doaj.art-96869b9c8eea4cdaa6df33ca4e2148242022-12-22T01:35:02ZengTermedia Publishing HousePolish Journal of Pathology1233-96872084-98692017-02-0167436436910.5114/pjp.2016.6587029479Patterns of glomerular disease based on 4-year kidney biopsy material analyzed by light microscopy and immunofluorescence: a retrospective single-center analysis in PolandAnna Olewicz-GawlikDorota SikorskaAgnieszka Pluto-PrądzyńskaMagdalena RoszakIlona Idasiak-PiechockaKrzysztof PawlaczykAndrzej OkoAldona WoźniakKatarzyna IwanikGrzegorz DworackiJan SikoraJan ŻeromskiThe aim of this study was to assess the epidemiology of different patterns of chronic glomerular diseases based on clinical, histopathological and immunofluorescent findings of glomerulonephritis patients hospitalized in the Department of Nephrology, Transplantology and Internal Diseases in Poznan between January 2009 and December 2012. We retrospectively studied 418 patients who had been subjected to renal biopsies. Data on serum creatinine concentration, 24 h proteinuria, arterial hypertension, diabetes mellitus, and histological and immunofluorescent findings were collected. The patients’ mean age was 42 ±15. The male sex prevailed (53.1%). Immunoglobulin A nephropathy was the most common finding (18.9%), followed by focal segmental glomerulosclerosis (16.3%), membranous glomerulonephritis (10.1%), lupus nephritis (8.4%), extracapillary glomerulonephritis (3.3%) and membranoproliferative glomerulonephritis (2.6%). In 69 (16.5%) patients the biopsy was non-informative or non-diagnostic. Patients with membranous nephropathy presented the highest frequency of nephrotic syndrome (71.4%), followed by membranoproliferative glomerulonephritis and focal segmental glomerulosclerosis. Combined analysis of the clinical, histopathological and immunofluorescent findings in glomerulonephritis patients based on a single center’s data can provide important epidemiological findings.https://www.termedia.pl/Patterns-of-glomerular-disease-based-on-4-year-kidney-biopsy-material-analyzed-by-light-microscopy-and-immunofluorescence-a-retrospective-single-center-analysis-in-Poland,55,29479,1,1.html: renal biopsy glomerulonephritis epidemiology |
| spellingShingle | Anna Olewicz-Gawlik Dorota Sikorska Agnieszka Pluto-Prądzyńska Magdalena Roszak Ilona Idasiak-Piechocka Krzysztof Pawlaczyk Andrzej Oko Aldona Woźniak Katarzyna Iwanik Grzegorz Dworacki Jan Sikora Jan Żeromski Patterns of glomerular disease based on 4-year kidney biopsy material analyzed by light microscopy and immunofluorescence: a retrospective single-center analysis in Poland Polish Journal of Pathology : renal biopsy glomerulonephritis epidemiology |
| title | Patterns of glomerular disease based on 4-year kidney biopsy material analyzed by light microscopy and immunofluorescence: a retrospective single-center analysis in Poland |
| title_full | Patterns of glomerular disease based on 4-year kidney biopsy material analyzed by light microscopy and immunofluorescence: a retrospective single-center analysis in Poland |
| title_fullStr | Patterns of glomerular disease based on 4-year kidney biopsy material analyzed by light microscopy and immunofluorescence: a retrospective single-center analysis in Poland |
| title_full_unstemmed | Patterns of glomerular disease based on 4-year kidney biopsy material analyzed by light microscopy and immunofluorescence: a retrospective single-center analysis in Poland |
| title_short | Patterns of glomerular disease based on 4-year kidney biopsy material analyzed by light microscopy and immunofluorescence: a retrospective single-center analysis in Poland |
| title_sort | patterns of glomerular disease based on 4 year kidney biopsy material analyzed by light microscopy and immunofluorescence a retrospective single center analysis in poland |
| topic | : renal biopsy glomerulonephritis epidemiology |
| url | https://www.termedia.pl/Patterns-of-glomerular-disease-based-on-4-year-kidney-biopsy-material-analyzed-by-light-microscopy-and-immunofluorescence-a-retrospective-single-center-analysis-in-Poland,55,29479,1,1.html |
| work_keys_str_mv | AT annaolewiczgawlik patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT dorotasikorska patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT agnieszkaplutopradzynska patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT magdalenaroszak patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT ilonaidasiakpiechocka patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT krzysztofpawlaczyk patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT andrzejoko patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT aldonawozniak patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT katarzynaiwanik patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT grzegorzdworacki patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT jansikora patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland AT janzeromski patternsofglomerulardiseasebasedon4yearkidneybiopsymaterialanalyzedbylightmicroscopyandimmunofluorescencearetrospectivesinglecenteranalysisinpoland |