GDF-11 promotes human trophoblast cell invasion by increasing ID2-mediated MMP2 expression

GDF-11 promotes human trophoblast cell invasion by increasing ID2-mediated MMP2 expression

Abstract Background Growth differentiation factor-11 (GDF-11), also known as bone morphogenetic protein-11, belongs to the transforming growth factor-beta superfamily. GDF-11 was first identified as an important regulator during embryonic development. Increasing evidence has demonstrated that GDF-11...

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Bibliographic Details
Main Authors: Ze Wu, Lanlan Fang, Sizhu Yang, Yibo Gao, Zhen Wang, Qingxue Meng, Xuan Dang, Ying-Pu Sun, Jung-Chien Cheng
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cell Communication and Signaling
Subjects:
GDF-11
BMP-11
MMP2
Trophoblast cells
Invasion
Online Access:https://doi.org/10.1186/s12964-022-00899-z

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