High-Throughput Monoclonal Antibody Discovery from Phage Libraries: Challenging the Current Preclinical Pipeline to Keep the Pace with the Increasing mAb Demand

High-Throughput Monoclonal Antibody Discovery from Phage Libraries: Challenging the Current Preclinical Pipeline to Keep the Pace with the Increasing mAb Demand

Monoclonal antibodies are among the most powerful therapeutics in modern medicine. Since the approval of the first therapeutic antibody in 1986, monoclonal antibodies keep holding great expectations for application in a range of clinical indications, highlighting the need to provide timely and susta...

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Bibliographic Details
Main Authors: Nicola Zambrano, Guendalina Froechlich, Dejan Lazarevic, Margherita Passariello, Alfredo Nicosia, Claudia De Lorenzo, Marco J. Morelli, Emanuele Sasso
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
monoclonal antibodies
high-throughput screening
next-generation sequencing
third-generation sequencing
target-unrelated
selection-unrelated
Online Access:https://www.mdpi.com/2072-6694/14/5/1325

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