Effect of Tai Chi versus aerobic exercise on blood pressure in prehypertension patients (TCOBPP): a study protocol for a 12-month single-blind randomized controlled trial
Abstract Background Compared with optimal blood pressure (BP), the prehypertension increases the risk of incident hypertension, cardiovascular (CV) events, and death. Moderate intensity of regular physical activity can reduce BP. However, aerobic exercise has some limitations. As a safe, low-impact,...
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | Trials |
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| Online Access: | https://doi.org/10.1186/s13063-022-06840-6 |
| _version_ | 1828164769686749184 |
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| author | Xinye Li Yonghong Gao Min Wu Dawei Wei Xingjiang Xiong Yan Yang Yuchen Jiang Xiandu Pan Ran Zhao Fan Yang Jiahao Sun Shengjie Yang Li Tian Linqiang Ban Xingye Li Peifen Chang Yanwei Xing |
| author_facet | Xinye Li Yonghong Gao Min Wu Dawei Wei Xingjiang Xiong Yan Yang Yuchen Jiang Xiandu Pan Ran Zhao Fan Yang Jiahao Sun Shengjie Yang Li Tian Linqiang Ban Xingye Li Peifen Chang Yanwei Xing |
| author_sort | Xinye Li |
| collection | DOAJ |
| description | Abstract Background Compared with optimal blood pressure (BP), the prehypertension increases the risk of incident hypertension, cardiovascular (CV) events, and death. Moderate intensity of regular physical activity can reduce BP. However, aerobic exercise has some limitations. As a safe, low-impact, enjoyable, and inexpensive form of exercise that requires minimal equipment and space, Tai Chi is expected as a viable alternative to aerobic exercise. The study aimed to assess the effect of Tai Chi intervention program, compared with aerobic exercise, on the BP in prehypertension patients. Methods This study is a 12-month, two-center, single-blind, parallel, randomized controlled trial. Three hundred forty-two patients with prehypertension [with a systolic blood pressure (SBP) in the range of 120 mmHg to 139 mmHg and/or a diastolic blood pressure (DBP) in the range of 80 mmHg to 89 mmHg] are randomized to one of two intervention groups in a 1:1 ratio: Tai Chi or aerobic exercise. BP monitoring methods of office blood pressure, ambulatory blood pressure monitoring (ABPM), and home blood pressure monitoring (HBPM) are used at the same time to detect BP in multiple dimensions. The primary outcome is the comparison of SBP change from baseline to 12 months in Tai Chi group and SBP change from baseline to 12 months in aerobic exercise group. The secondary endpoints are as following: (1) the comparison of DBP of office blood pressure change from baseline to 12 months between Tai Chi group and aerobic exercise group, (2) the comparison of BP and the variability of BP assessed through ABPM change from baseline to 12 months between Tai Chi group and aerobic exercise group, (3) the comparison of BP assessed through HBPM change from baseline to 12 months between Tai Chi group and aerobic exercise group. Discussion This will be the first randomized controlled trial to specifically study the benefits of Tai Chi on the blood pressure control in patients with prehypertension. The successful completion of this study will help to provide evidence for whether Tai Chi is more desirable than aerobic exercise. Trial registration Trial registration number: Chinese Clinical Trial Registry, ChiCTR1900024368. Registered on 7 July 2019, http://www.chictr.org.cn/edit.aspx?pid=39478&htm=4 |
| first_indexed | 2024-04-12T01:32:01Z |
| format | Article |
| id | doaj.art-9690d3ee586d4190abdd1220f75587e0 |
| institution | Directory Open Access Journal |
| issn | 1745-6215 |
| language | English |
| last_indexed | 2024-04-12T01:32:01Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Trials |
| spelling | doaj.art-9690d3ee586d4190abdd1220f75587e02022-12-22T03:53:27ZengBMCTrials1745-62152022-12-0123111410.1186/s13063-022-06840-6Effect of Tai Chi versus aerobic exercise on blood pressure in prehypertension patients (TCOBPP): a study protocol for a 12-month single-blind randomized controlled trialXinye Li0Yonghong Gao1Min Wu2Dawei Wei3Xingjiang Xiong4Yan Yang5Yuchen Jiang6Xiandu Pan7Ran Zhao8Fan Yang9Jiahao Sun10Shengjie Yang11Li Tian12Linqiang Ban13Xingye Li14Peifen Chang15Yanwei Xing16Beijing University of Chinese MedicineKey Laboratory of Chinese Internal Medicine of the Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese MedicineGuang’anmen Hospital, China Academy of Chinese Medical SciencesBeijing University of Chinese MedicineGuang’anmen Hospital, China Academy of Chinese Medical SciencesBeijing University of Chinese MedicineGuang’anmen Hospital, China Academy of Chinese Medical SciencesBeijing University of Chinese MedicineBeijing University of Chinese MedicineGuang’anmen Hospital, China Academy of Chinese Medical SciencesBeijing University of Chinese MedicineGuang’anmen Hospital, China Academy of Chinese Medical SciencesBeijing University of Chinese MedicineBeijing University of Chinese MedicineBeijing University of Chinese MedicineDongzhimen Hospital Affiliated to Beijing University of Chinese MedicineGuang’anmen Hospital, China Academy of Chinese Medical SciencesAbstract Background Compared with optimal blood pressure (BP), the prehypertension increases the risk of incident hypertension, cardiovascular (CV) events, and death. Moderate intensity of regular physical activity can reduce BP. However, aerobic exercise has some limitations. As a safe, low-impact, enjoyable, and inexpensive form of exercise that requires minimal equipment and space, Tai Chi is expected as a viable alternative to aerobic exercise. The study aimed to assess the effect of Tai Chi intervention program, compared with aerobic exercise, on the BP in prehypertension patients. Methods This study is a 12-month, two-center, single-blind, parallel, randomized controlled trial. Three hundred forty-two patients with prehypertension [with a systolic blood pressure (SBP) in the range of 120 mmHg to 139 mmHg and/or a diastolic blood pressure (DBP) in the range of 80 mmHg to 89 mmHg] are randomized to one of two intervention groups in a 1:1 ratio: Tai Chi or aerobic exercise. BP monitoring methods of office blood pressure, ambulatory blood pressure monitoring (ABPM), and home blood pressure monitoring (HBPM) are used at the same time to detect BP in multiple dimensions. The primary outcome is the comparison of SBP change from baseline to 12 months in Tai Chi group and SBP change from baseline to 12 months in aerobic exercise group. The secondary endpoints are as following: (1) the comparison of DBP of office blood pressure change from baseline to 12 months between Tai Chi group and aerobic exercise group, (2) the comparison of BP and the variability of BP assessed through ABPM change from baseline to 12 months between Tai Chi group and aerobic exercise group, (3) the comparison of BP assessed through HBPM change from baseline to 12 months between Tai Chi group and aerobic exercise group. Discussion This will be the first randomized controlled trial to specifically study the benefits of Tai Chi on the blood pressure control in patients with prehypertension. The successful completion of this study will help to provide evidence for whether Tai Chi is more desirable than aerobic exercise. Trial registration Trial registration number: Chinese Clinical Trial Registry, ChiCTR1900024368. Registered on 7 July 2019, http://www.chictr.org.cn/edit.aspx?pid=39478&htm=4https://doi.org/10.1186/s13063-022-06840-6Tai ChiAerobic exercisePrehypertensionBlood pressure |
| spellingShingle | Xinye Li Yonghong Gao Min Wu Dawei Wei Xingjiang Xiong Yan Yang Yuchen Jiang Xiandu Pan Ran Zhao Fan Yang Jiahao Sun Shengjie Yang Li Tian Linqiang Ban Xingye Li Peifen Chang Yanwei Xing Effect of Tai Chi versus aerobic exercise on blood pressure in prehypertension patients (TCOBPP): a study protocol for a 12-month single-blind randomized controlled trial Trials Tai Chi Aerobic exercise Prehypertension Blood pressure |
| title | Effect of Tai Chi versus aerobic exercise on blood pressure in prehypertension patients (TCOBPP): a study protocol for a 12-month single-blind randomized controlled trial |
| title_full | Effect of Tai Chi versus aerobic exercise on blood pressure in prehypertension patients (TCOBPP): a study protocol for a 12-month single-blind randomized controlled trial |
| title_fullStr | Effect of Tai Chi versus aerobic exercise on blood pressure in prehypertension patients (TCOBPP): a study protocol for a 12-month single-blind randomized controlled trial |
| title_full_unstemmed | Effect of Tai Chi versus aerobic exercise on blood pressure in prehypertension patients (TCOBPP): a study protocol for a 12-month single-blind randomized controlled trial |
| title_short | Effect of Tai Chi versus aerobic exercise on blood pressure in prehypertension patients (TCOBPP): a study protocol for a 12-month single-blind randomized controlled trial |
| title_sort | effect of tai chi versus aerobic exercise on blood pressure in prehypertension patients tcobpp a study protocol for a 12 month single blind randomized controlled trial |
| topic | Tai Chi Aerobic exercise Prehypertension Blood pressure |
| url | https://doi.org/10.1186/s13063-022-06840-6 |
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