Thyroid dysfunction in type 2 diabetes mellitus: A retrospective study
Introduction: Type 2 diabetes mellitus (DM) is a growing problem in our country and we have observed that many patients are associated with thyroid dysfunction later in their life. However, the prevalence of thyroid dysfunction in these patients has not been investigated. Aims and Objectives: To fin...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2012-01-01
|
| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=8;spage=334;epage=335;aulast=Demitrost |
| _version_ | 1818011224798920704 |
|---|---|
| author | Laloo Demitrost Salam Ranabir |
| author_facet | Laloo Demitrost Salam Ranabir |
| author_sort | Laloo Demitrost |
| collection | DOAJ |
| description | Introduction: Type 2 diabetes mellitus (DM) is a growing problem in our country and we have observed that many patients are associated with thyroid dysfunction later in their life. However, the prevalence of thyroid dysfunction in these patients has not been investigated. Aims and Objectives: To find the prevalence of thyroid dysfunction in type 2 DM in Manipur, India. Materials and Methods: In this retrospective study, data of 202 Type 2 DM patients who attended the diabetic clinic of the Regional Institute of Medical Sciences, Imphal from January 2011 to July 2012, and whose thyroid stimulating hormone (TSH) level was investigated were included. The inclusion criteria are known cases of type 2 DM. Exclusion criteria are patients with previous history of hypothyroidism and those on drugs affecting the thyroid profile. Results: Out the 202 type 2 DM patients for the study of which 61 are males and 141 are females, 139 (68.8%) are euthyroid, 33 (16.3%) have subclinical hypothyroidism (10 males and 23 females), 23 (11.4%) have hypothyroidism (6 males and 17 females), 4 (2%) have subclinical hyperthyroidism and 3 (1.5%) are hyperthyroidism cases. Maximum cases were of hypothyroidism (subclinical and clinical) seen in the age group of 45-64 years. Patients with BMI > 25 were at increased risk of having hypothyroidism (P < 0.016). Conclusion: Prevalence of hypothyroidism is quite high in type 2 DM patients above 45 years and more so if their BMI is over 25. |
| first_indexed | 2024-04-14T06:04:52Z |
| format | Article |
| id | doaj.art-96940475b4cb4abfbe156248f9e5a527 |
| institution | Directory Open Access Journal |
| issn | 2230-8210 2230-9500 |
| language | English |
| last_indexed | 2024-04-14T06:04:52Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-96940475b4cb4abfbe156248f9e5a5272022-12-22T02:08:34ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002012-01-0116833433510.4103/2230-8210.104080Thyroid dysfunction in type 2 diabetes mellitus: A retrospective studyLaloo DemitrostSalam RanabirIntroduction: Type 2 diabetes mellitus (DM) is a growing problem in our country and we have observed that many patients are associated with thyroid dysfunction later in their life. However, the prevalence of thyroid dysfunction in these patients has not been investigated. Aims and Objectives: To find the prevalence of thyroid dysfunction in type 2 DM in Manipur, India. Materials and Methods: In this retrospective study, data of 202 Type 2 DM patients who attended the diabetic clinic of the Regional Institute of Medical Sciences, Imphal from January 2011 to July 2012, and whose thyroid stimulating hormone (TSH) level was investigated were included. The inclusion criteria are known cases of type 2 DM. Exclusion criteria are patients with previous history of hypothyroidism and those on drugs affecting the thyroid profile. Results: Out the 202 type 2 DM patients for the study of which 61 are males and 141 are females, 139 (68.8%) are euthyroid, 33 (16.3%) have subclinical hypothyroidism (10 males and 23 females), 23 (11.4%) have hypothyroidism (6 males and 17 females), 4 (2%) have subclinical hyperthyroidism and 3 (1.5%) are hyperthyroidism cases. Maximum cases were of hypothyroidism (subclinical and clinical) seen in the age group of 45-64 years. Patients with BMI > 25 were at increased risk of having hypothyroidism (P < 0.016). Conclusion: Prevalence of hypothyroidism is quite high in type 2 DM patients above 45 years and more so if their BMI is over 25.http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=8;spage=334;epage=335;aulast=DemitrostTSHthyroid dysfunctiontype 2 DM |
| spellingShingle | Laloo Demitrost Salam Ranabir Thyroid dysfunction in type 2 diabetes mellitus: A retrospective study Indian Journal of Endocrinology and Metabolism TSH thyroid dysfunction type 2 DM |
| title | Thyroid dysfunction in type 2 diabetes mellitus: A retrospective study |
| title_full | Thyroid dysfunction in type 2 diabetes mellitus: A retrospective study |
| title_fullStr | Thyroid dysfunction in type 2 diabetes mellitus: A retrospective study |
| title_full_unstemmed | Thyroid dysfunction in type 2 diabetes mellitus: A retrospective study |
| title_short | Thyroid dysfunction in type 2 diabetes mellitus: A retrospective study |
| title_sort | thyroid dysfunction in type 2 diabetes mellitus a retrospective study |
| topic | TSH thyroid dysfunction type 2 DM |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=8;spage=334;epage=335;aulast=Demitrost |
| work_keys_str_mv | AT laloodemitrost thyroiddysfunctionintype2diabetesmellitusaretrospectivestudy AT salamranabir thyroiddysfunctionintype2diabetesmellitusaretrospectivestudy |