Primary aldosteronism and obstructive sleep apnea: What do we know thus far?

Both primary aldosteronism and obstructive sleep apnea are well-known causes of hypertension and contribute to increased cardiovascular morbidity and mortality independently. However, the relationship between these two entities remains unclear, with studies demonstrating contradictory results. This...

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Main Authors: Huai Heng Loh, Norlela Sukor
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.976979/full
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author Huai Heng Loh
Huai Heng Loh
Norlela Sukor
author_facet Huai Heng Loh
Huai Heng Loh
Norlela Sukor
author_sort Huai Heng Loh
collection DOAJ
description Both primary aldosteronism and obstructive sleep apnea are well-known causes of hypertension and contribute to increased cardiovascular morbidity and mortality independently. However, the relationship between these two entities remains unclear, with studies demonstrating contradictory results. This review aims to collate and put into perspective current available research regarding the association between primary aldosteronism and obstructive sleep apnea. The relationship between these two entities, clinical characteristics, clinical implications, outcomes of treatment, potential causal links and mechanisms are hereby presented.
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spelling doaj.art-96945282fa0a4edf92eb4398400922f42022-12-22T02:00:41ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-09-011310.3389/fendo.2022.976979976979Primary aldosteronism and obstructive sleep apnea: What do we know thus far?Huai Heng Loh0Huai Heng Loh1Norlela Sukor2Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center (UKMMC), Kuala Lumpur, MalaysiaDepartment of Medicine, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Sarawak, Kota Samarahan, MalaysiaDepartment of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center (UKMMC), Kuala Lumpur, MalaysiaBoth primary aldosteronism and obstructive sleep apnea are well-known causes of hypertension and contribute to increased cardiovascular morbidity and mortality independently. However, the relationship between these two entities remains unclear, with studies demonstrating contradictory results. This review aims to collate and put into perspective current available research regarding the association between primary aldosteronism and obstructive sleep apnea. The relationship between these two entities, clinical characteristics, clinical implications, outcomes of treatment, potential causal links and mechanisms are hereby presented.https://www.frontiersin.org/articles/10.3389/fendo.2022.976979/fullreninangiotensinaldosteronesleep disordersobesityhypertension
spellingShingle Huai Heng Loh
Huai Heng Loh
Norlela Sukor
Primary aldosteronism and obstructive sleep apnea: What do we know thus far?
Frontiers in Endocrinology
renin
angiotensin
aldosterone
sleep disorders
obesity
hypertension
title Primary aldosteronism and obstructive sleep apnea: What do we know thus far?
title_full Primary aldosteronism and obstructive sleep apnea: What do we know thus far?
title_fullStr Primary aldosteronism and obstructive sleep apnea: What do we know thus far?
title_full_unstemmed Primary aldosteronism and obstructive sleep apnea: What do we know thus far?
title_short Primary aldosteronism and obstructive sleep apnea: What do we know thus far?
title_sort primary aldosteronism and obstructive sleep apnea what do we know thus far
topic renin
angiotensin
aldosterone
sleep disorders
obesity
hypertension
url https://www.frontiersin.org/articles/10.3389/fendo.2022.976979/full
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AT norlelasukor primaryaldosteronismandobstructivesleepapneawhatdoweknowthusfar