Identifying the Internalizing Disorder Clusters Among Recently Hospitalized Cardiovascular Disease Patients: A Receiver Operating Characteristics Study

Depression and anxiety disorders are common among cardiovascular disease (CVD) populations, leading several cardiology societies to recommend routine screening to streamline psychological interventions. However, it remains poorly understood whether routine screening in CVD populations identifies the...

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Main Authors: Megan Grech, Deborah A. Turnbull, Gary A. Wittert, Phillip J. Tully, the CHAMPS Investigators, John D. Horowitz, John F. Beltrame, Alison Barrett, Nathan Harrison, Christopher Bean, Terina Selkow, Libby Markwick, Bernhard T. Baune, Harald Baumeister, Shannon Sauer-Zavala
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Psychology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fpsyg.2019.02829/full
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author Megan Grech
Megan Grech
Deborah A. Turnbull
Deborah A. Turnbull
Gary A. Wittert
Phillip J. Tully
the CHAMPS Investigators
John D. Horowitz
John F. Beltrame
Alison Barrett
Nathan Harrison
Christopher Bean
John F. Beltrame
Terina Selkow
Libby Markwick
Bernhard T. Baune
Harald Baumeister
Shannon Sauer-Zavala
author_facet Megan Grech
Megan Grech
Deborah A. Turnbull
Deborah A. Turnbull
Gary A. Wittert
Phillip J. Tully
the CHAMPS Investigators
John D. Horowitz
John F. Beltrame
Alison Barrett
Nathan Harrison
Christopher Bean
John F. Beltrame
Terina Selkow
Libby Markwick
Bernhard T. Baune
Harald Baumeister
Shannon Sauer-Zavala
author_sort Megan Grech
collection DOAJ
description Depression and anxiety disorders are common among cardiovascular disease (CVD) populations, leading several cardiology societies to recommend routine screening to streamline psychological interventions. However, it remains poorly understood whether routine screening in CVD populations identifies the broader groups of disorders that cluster together within individuals, known as anxious-misery and fear. This study examines the screening utility of four anxiety and depression questionnaires to identify the two internalizing disorder clusters; anxious-misery and fear. Patients with a recent hospital admission for CVD (n = 85, 69.4% males) underwent a structured clinical interview with the MINI International Neuropsychiatric Interview. The participants also completed the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder (GAD-7) scale, Overall Anxiety Severity Impairment Scale (OASIS), and the stress subscale of the Depression Anxiety Stress Scale (DASS). The PHQ-9 and the GAD-7 yielded appropriate screening properties to detect three different iterations of the anxious-misery cluster (sensitivity >80.95% and specificity >82.81%). The GAD-7 was the only instrument to display favorable screening properties to detect a fear cluster omitting post-traumatic stress disorder (PTSD) but including obsessive-compulsive disorder (OCD; sensitivity 81.25%, specificity 76.81%). These findings indicate that the PHQ-9 and GAD-7 could be implemented to reliably screen for anxious-misery disorders among CVD in-patients, however, the receiver operating characteristics (ROC) to detect fear disorders were contingent on the placement of PTSD and OCD within clusters. The findings are discussed in relation to routine screening guidelines in CVD populations and contemporary understandings of the internalizing disorders.
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spelling doaj.art-969a2b416b244f03aa8e98f574490d3a2022-12-22T02:03:22ZengFrontiers Media S.A.Frontiers in Psychology1664-10782019-12-011010.3389/fpsyg.2019.02829483754Identifying the Internalizing Disorder Clusters Among Recently Hospitalized Cardiovascular Disease Patients: A Receiver Operating Characteristics StudyMegan Grech0Megan Grech1Deborah A. Turnbull2Deborah A. Turnbull3Gary A. Wittert4Phillip J. Tully5the CHAMPS InvestigatorsJohn D. HorowitzJohn F. BeltrameAlison BarrettNathan HarrisonChristopher BeanJohn F. BeltrameTerina SelkowLibby MarkwickBernhard T. BauneHarald BaumeisterShannon Sauer-ZavalaSchool of Psychology, The University of Adelaide, Adelaide, SA, AustraliaFreemasons Foundation Centre for Men’s Health, School of Medicine, The University of Adelaide, Adelaide, SA, AustraliaSchool of Psychology, The University of Adelaide, Adelaide, SA, AustraliaFreemasons Foundation Centre for Men’s Health, School of Medicine, The University of Adelaide, Adelaide, SA, AustraliaFreemasons Foundation Centre for Men’s Health, School of Medicine, The University of Adelaide, Adelaide, SA, AustraliaFreemasons Foundation Centre for Men’s Health, School of Medicine, The University of Adelaide, Adelaide, SA, AustraliaDepression and anxiety disorders are common among cardiovascular disease (CVD) populations, leading several cardiology societies to recommend routine screening to streamline psychological interventions. However, it remains poorly understood whether routine screening in CVD populations identifies the broader groups of disorders that cluster together within individuals, known as anxious-misery and fear. This study examines the screening utility of four anxiety and depression questionnaires to identify the two internalizing disorder clusters; anxious-misery and fear. Patients with a recent hospital admission for CVD (n = 85, 69.4% males) underwent a structured clinical interview with the MINI International Neuropsychiatric Interview. The participants also completed the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder (GAD-7) scale, Overall Anxiety Severity Impairment Scale (OASIS), and the stress subscale of the Depression Anxiety Stress Scale (DASS). The PHQ-9 and the GAD-7 yielded appropriate screening properties to detect three different iterations of the anxious-misery cluster (sensitivity >80.95% and specificity >82.81%). The GAD-7 was the only instrument to display favorable screening properties to detect a fear cluster omitting post-traumatic stress disorder (PTSD) but including obsessive-compulsive disorder (OCD; sensitivity 81.25%, specificity 76.81%). These findings indicate that the PHQ-9 and GAD-7 could be implemented to reliably screen for anxious-misery disorders among CVD in-patients, however, the receiver operating characteristics (ROC) to detect fear disorders were contingent on the placement of PTSD and OCD within clusters. The findings are discussed in relation to routine screening guidelines in CVD populations and contemporary understandings of the internalizing disorders.https://www.frontiersin.org/article/10.3389/fpsyg.2019.02829/fulldepressionanxietyinternalizing disordersreceiver operating characteristicscardiovascular diseasepost-traumatic stress disorder
spellingShingle Megan Grech
Megan Grech
Deborah A. Turnbull
Deborah A. Turnbull
Gary A. Wittert
Phillip J. Tully
the CHAMPS Investigators
John D. Horowitz
John F. Beltrame
Alison Barrett
Nathan Harrison
Christopher Bean
John F. Beltrame
Terina Selkow
Libby Markwick
Bernhard T. Baune
Harald Baumeister
Shannon Sauer-Zavala
Identifying the Internalizing Disorder Clusters Among Recently Hospitalized Cardiovascular Disease Patients: A Receiver Operating Characteristics Study
Frontiers in Psychology
depression
anxiety
internalizing disorders
receiver operating characteristics
cardiovascular disease
post-traumatic stress disorder
title Identifying the Internalizing Disorder Clusters Among Recently Hospitalized Cardiovascular Disease Patients: A Receiver Operating Characteristics Study
title_full Identifying the Internalizing Disorder Clusters Among Recently Hospitalized Cardiovascular Disease Patients: A Receiver Operating Characteristics Study
title_fullStr Identifying the Internalizing Disorder Clusters Among Recently Hospitalized Cardiovascular Disease Patients: A Receiver Operating Characteristics Study
title_full_unstemmed Identifying the Internalizing Disorder Clusters Among Recently Hospitalized Cardiovascular Disease Patients: A Receiver Operating Characteristics Study
title_short Identifying the Internalizing Disorder Clusters Among Recently Hospitalized Cardiovascular Disease Patients: A Receiver Operating Characteristics Study
title_sort identifying the internalizing disorder clusters among recently hospitalized cardiovascular disease patients a receiver operating characteristics study
topic depression
anxiety
internalizing disorders
receiver operating characteristics
cardiovascular disease
post-traumatic stress disorder
url https://www.frontiersin.org/article/10.3389/fpsyg.2019.02829/full
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