Tyrosine Kinase Inhibitors in Adult Glioblastoma: An (Un)Closed Chapter?

Tyrosine Kinase Inhibitors in Adult Glioblastoma: An (Un)Closed Chapter?

Glioblastoma (GBM) is the most common and lethal form of malignant brain tumor. GBM patients normally undergo surgery plus adjuvant radiotherapy followed by chemotherapy. Numerous studies into the molecular events driving GBM highlight the central role played by the Epidermal Growth Factor Receptor...

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Bibliographic Details
Main Authors: Paula Aldaz, Imanol Arozarena
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
glioblastoma
receptor tyrosine kinase
tyrosine kinase inhibitors
targeted therapy
Online Access:https://www.mdpi.com/2072-6694/13/22/5799

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