An Atypical ABC Transporter Is Involved in Antifungal Resistance and Host Interactions in the Pathogenic Fungus Cryptococcus neoformans

An Atypical ABC Transporter Is Involved in Antifungal Resistance and Host Interactions in the Pathogenic Fungus Cryptococcus neoformans

ABSTRACT ATP-binding cassette (ABC) transporters represent one of the largest protein superfamilies. Functionally diverse, ABC transporters have been implicated in many aspects of microbial physiology. The genome of the human fungal pathogen Cryptococcus neoformans encodes 54 putative ABC transporte...

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Bibliographic Details
Main Authors: Christopher J. Winski, Yuanyuan Qian, Shahriar Mobashery, Felipe H. Santiago-Tirado
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:mBio
Subjects:
ABC transporters
Cryptococcus neoformans
antifungal resistance
host-pathogen interactions
Online Access:https://journals.asm.org/doi/10.1128/mbio.01539-22

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