Neurogranin and Neurofilament Light Chain as Preclinical Biomarkers in Scrapie

Neurogranin and Neurofilament Light Chain as Preclinical Biomarkers in Scrapie

Prion diseases are diagnosed in the symptomatic stage, when the neuronal damage is spread throughout the central nervous system (CNS). The assessment of biological features that allow the detection of asymptomatic cases is needed, and, in this context, scrapie, where pre-symptomatic infected animals...

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Bibliographic Details
Main Authors: Marina Betancor, Sonia Pérez-Lázaro, Alicia Otero, Belén Marín, Inmaculada Martín-Burriel, Kaj Blennow, Juan José Badiola, Henrik Zetterberg, Rosa Bolea
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
prion
prion diseases
scrapie
biomarkers
neurodegeneration
neurogranin
Online Access:https://www.mdpi.com/1422-0067/23/13/7182

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