Negative pressure wound therapy for flap closed-incisions after 3D-printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defects
Abstract Background The flap closed-incisions healing after 3D-printed prosthesis implantation in Chronic Osteomyelitis with Soft Tissue Defects (COSTD) is critical. This study aimed to explore the safety and effectiveness of Negative Pressure Wound Therapy (NPWT) in promoting flap closed-incisions...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-023-06970-1 |
| _version_ | 1797578612898004992 |
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| author | Zhiyu Lin Xinling Zhang Yujie Chen Yun Tian Xin Yang Zhenmin Zhao |
| author_facet | Zhiyu Lin Xinling Zhang Yujie Chen Yun Tian Xin Yang Zhenmin Zhao |
| author_sort | Zhiyu Lin |
| collection | DOAJ |
| description | Abstract Background The flap closed-incisions healing after 3D-printed prosthesis implantation in Chronic Osteomyelitis with Soft Tissue Defects (COSTD) is critical. This study aimed to explore the safety and effectiveness of Negative Pressure Wound Therapy (NPWT) in promoting flap closed-incisions healing. Methods Retrospective analysis of clinical data was performed, including baseline, surgical and hospitalization information. The efficacy of NPWT was assessed by comparing the ASEPSIS scores, Visual Analogue Scale (VAS), Activity of Daily Living Scale (ADLS), and Lower Extremity Functional Scale (LEFS), as well as the major postoperative complications. Results The study included 20 patients, 13 received conventional dressing (Control group) and 7 received NPWT treatment (NPWT group). These two groups exhibited a notable disparity in the distribution of ASEPSIS scores, and the median scores were 24 in Control group and 9 in NPWT group (p = 0.001). Eight patients in the Control group experienced major incisional complications, including 7 cases of exudation, 3 cases of infection, 2 cases of non-healing, and 1 case of dehiscence, while none were observed in the NPWT group (p = 0.015). The VAS, ADLS, and LEFS scores were significantly improved in the NPWT group compared to the Control group (p = 0.003, 0.017, and 0.043, respectively). Conclusions The study findings suggest that NPWT applied to the healing process of flap closed-incisions after 3D prosthesis implantation in patients with COSTD can reduce the occurrence of postoperative major complications and promote the recovery of lower limb function and daily activities, which should be recommended for clinical practice. |
| first_indexed | 2024-03-10T22:24:20Z |
| format | Article |
| id | doaj.art-96b14b67d20041f3b3ed85d532f6cc49 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-03-10T22:24:20Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-96b14b67d20041f3b3ed85d532f6cc492023-11-19T12:09:31ZengBMCBMC Musculoskeletal Disorders1471-24742023-10-0124111110.1186/s12891-023-06970-1Negative pressure wound therapy for flap closed-incisions after 3D-printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defectsZhiyu Lin0Xinling Zhang1Yujie Chen2Yun Tian3Xin Yang4Zhenmin Zhao5Department of Plastic Surgery , Peking University Third HospitalDepartment of Plastic Surgery, Beijing HospitalDepartment of Plastic Surgery , Peking University Third HospitalDepartment of Orthopaedics, Peking University Third HospitalDepartment of Plastic Surgery , Peking University Third HospitalDepartment of Plastic Surgery , Peking University Third HospitalAbstract Background The flap closed-incisions healing after 3D-printed prosthesis implantation in Chronic Osteomyelitis with Soft Tissue Defects (COSTD) is critical. This study aimed to explore the safety and effectiveness of Negative Pressure Wound Therapy (NPWT) in promoting flap closed-incisions healing. Methods Retrospective analysis of clinical data was performed, including baseline, surgical and hospitalization information. The efficacy of NPWT was assessed by comparing the ASEPSIS scores, Visual Analogue Scale (VAS), Activity of Daily Living Scale (ADLS), and Lower Extremity Functional Scale (LEFS), as well as the major postoperative complications. Results The study included 20 patients, 13 received conventional dressing (Control group) and 7 received NPWT treatment (NPWT group). These two groups exhibited a notable disparity in the distribution of ASEPSIS scores, and the median scores were 24 in Control group and 9 in NPWT group (p = 0.001). Eight patients in the Control group experienced major incisional complications, including 7 cases of exudation, 3 cases of infection, 2 cases of non-healing, and 1 case of dehiscence, while none were observed in the NPWT group (p = 0.015). The VAS, ADLS, and LEFS scores were significantly improved in the NPWT group compared to the Control group (p = 0.003, 0.017, and 0.043, respectively). Conclusions The study findings suggest that NPWT applied to the healing process of flap closed-incisions after 3D prosthesis implantation in patients with COSTD can reduce the occurrence of postoperative major complications and promote the recovery of lower limb function and daily activities, which should be recommended for clinical practice.https://doi.org/10.1186/s12891-023-06970-1Chronic osteomyelitisClosed-incisionNegative pressure wound therapySoft tissue defects |
| spellingShingle | Zhiyu Lin Xinling Zhang Yujie Chen Yun Tian Xin Yang Zhenmin Zhao Negative pressure wound therapy for flap closed-incisions after 3D-printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defects BMC Musculoskeletal Disorders Chronic osteomyelitis Closed-incision Negative pressure wound therapy Soft tissue defects |
| title | Negative pressure wound therapy for flap closed-incisions after 3D-printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defects |
| title_full | Negative pressure wound therapy for flap closed-incisions after 3D-printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defects |
| title_fullStr | Negative pressure wound therapy for flap closed-incisions after 3D-printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defects |
| title_full_unstemmed | Negative pressure wound therapy for flap closed-incisions after 3D-printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defects |
| title_short | Negative pressure wound therapy for flap closed-incisions after 3D-printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defects |
| title_sort | negative pressure wound therapy for flap closed incisions after 3d printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defects |
| topic | Chronic osteomyelitis Closed-incision Negative pressure wound therapy Soft tissue defects |
| url | https://doi.org/10.1186/s12891-023-06970-1 |
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