Role of e-cigarettes and pharmacotherapy during attempts to quit cigarette smoking: The PATH Study 2013-16.
<h4>Background</h4>More smokers report using e-cigarettes to help them quit than FDA-approved pharmacotherapy.<h4>Objective</h4>To assess the association of e-cigarettes with future abstinence from cigarette and tobacco use.<h4>Design</h4>Cohort study of US sample...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
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Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0237938 |
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author | John P Pierce Tarik Benmarhnia Ruifeng Chen Martha White David B Abrams Bridget K Ambrose Carlos Blanco Nicolette Borek Kelvin Choi Blair Coleman Wilson M Compton K Michael Cummings Cristine D Delnevo Tara Elton-Marshall Maciej L Goniewicz Shannon Gravely Geoffrey T Fong Dorothy Hatsukami James Henrie Karin A Kasza Sheila Kealey Heather L Kimmel Jean Limpert Raymond S Niaura Carolina Ramôa Eva Sharma Marushka L Silveira Cassandra A Stanton Michael B Steinberg Ethel Taylor Maansi Bansal-Travers Dennis R Trinidad Lisa D Gardner Andrew Hyland Samir Soneji Karen Messer |
author_facet | John P Pierce Tarik Benmarhnia Ruifeng Chen Martha White David B Abrams Bridget K Ambrose Carlos Blanco Nicolette Borek Kelvin Choi Blair Coleman Wilson M Compton K Michael Cummings Cristine D Delnevo Tara Elton-Marshall Maciej L Goniewicz Shannon Gravely Geoffrey T Fong Dorothy Hatsukami James Henrie Karin A Kasza Sheila Kealey Heather L Kimmel Jean Limpert Raymond S Niaura Carolina Ramôa Eva Sharma Marushka L Silveira Cassandra A Stanton Michael B Steinberg Ethel Taylor Maansi Bansal-Travers Dennis R Trinidad Lisa D Gardner Andrew Hyland Samir Soneji Karen Messer |
author_sort | John P Pierce |
collection | DOAJ |
description | <h4>Background</h4>More smokers report using e-cigarettes to help them quit than FDA-approved pharmacotherapy.<h4>Objective</h4>To assess the association of e-cigarettes with future abstinence from cigarette and tobacco use.<h4>Design</h4>Cohort study of US sample, with annual follow-up.<h4>Participants</h4>US adult (ages 18+) daily cigarette smokers identified at Wave 1 (W1; 2013-14) of the PATH Study, who reported a quit attempt before W2 and completed W3 (n = 2443).<h4>Exposures</h4>Use of e-cigarettes, pharmacotherapy (including nicotine replacement therapy), or no product for last quit attempt (LQA), and current daily e-cigarette use at W2.<h4>Analysis</h4>Propensity score matching (PSM) of groups using different methods to quit.<h4>Outcome measures</h4>12+ months abstinence at W3 from cigarettes and from all tobacco (including e-cigarettes). 30+ days abstinence at W3 was a secondary outcome.<h4>Results</h4>Among daily smokers with an LQA, 23.5% used e-cigarettes, 19.3% used pharmacotherapy only (including NRT) and 57.2% used no product. Cigarette abstinence for 12+ months at W3 was ~10% in each group. Half of the cigarette abstainers in the e-cigarette group were using e-cigarettes at W3. Different methods to help quitting had statistically comparable 12+ month cigarette abstinence at W3 (e-cigarettes vs no product: Risk Difference (RD) = 0.01, 95% CI: -0.04 to 0.06; e-cigarettes vs pharmacotherapy: RD = 0.02, 95% CI:-0.04 to 0.09). Likewise, daily e-cigarette users at W2 did not show a cessation benefit over comparable no-e-cigarette users and this finding was robust to sensitivity analyses. Abstinence for 30+ days at W3 was also similar across products.<h4>Limitations</h4>The frequency of e-cigarette use during the LQA was not assessed, nor was it possible to assess continuous abstinence from the LQA.<h4>Conclusion</h4>Among US daily smokers who quit cigarettes in 2014-15, use of e-cigarettes in that attempt compared to approved cessation aids or no products showed similar abstinence rates 1-2 years later. |
first_indexed | 2024-12-19T17:46:13Z |
format | Article |
id | doaj.art-96bebcf6dec34f568533a215f6999d4d |
institution | Directory Open Access Journal |
issn | 1932-6203 |
language | English |
last_indexed | 2024-12-19T17:46:13Z |
publishDate | 2020-01-01 |
publisher | Public Library of Science (PLoS) |
record_format | Article |
series | PLoS ONE |
spelling | doaj.art-96bebcf6dec34f568533a215f6999d4d2022-12-21T20:12:03ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-01159e023793810.1371/journal.pone.0237938Role of e-cigarettes and pharmacotherapy during attempts to quit cigarette smoking: The PATH Study 2013-16.John P PierceTarik BenmarhniaRuifeng ChenMartha WhiteDavid B AbramsBridget K AmbroseCarlos BlancoNicolette BorekKelvin ChoiBlair ColemanWilson M ComptonK Michael CummingsCristine D DelnevoTara Elton-MarshallMaciej L GoniewiczShannon GravelyGeoffrey T FongDorothy HatsukamiJames HenrieKarin A KaszaSheila KealeyHeather L KimmelJean LimpertRaymond S NiauraCarolina RamôaEva SharmaMarushka L SilveiraCassandra A StantonMichael B SteinbergEthel TaylorMaansi Bansal-TraversDennis R TrinidadLisa D GardnerAndrew HylandSamir SonejiKaren Messer<h4>Background</h4>More smokers report using e-cigarettes to help them quit than FDA-approved pharmacotherapy.<h4>Objective</h4>To assess the association of e-cigarettes with future abstinence from cigarette and tobacco use.<h4>Design</h4>Cohort study of US sample, with annual follow-up.<h4>Participants</h4>US adult (ages 18+) daily cigarette smokers identified at Wave 1 (W1; 2013-14) of the PATH Study, who reported a quit attempt before W2 and completed W3 (n = 2443).<h4>Exposures</h4>Use of e-cigarettes, pharmacotherapy (including nicotine replacement therapy), or no product for last quit attempt (LQA), and current daily e-cigarette use at W2.<h4>Analysis</h4>Propensity score matching (PSM) of groups using different methods to quit.<h4>Outcome measures</h4>12+ months abstinence at W3 from cigarettes and from all tobacco (including e-cigarettes). 30+ days abstinence at W3 was a secondary outcome.<h4>Results</h4>Among daily smokers with an LQA, 23.5% used e-cigarettes, 19.3% used pharmacotherapy only (including NRT) and 57.2% used no product. Cigarette abstinence for 12+ months at W3 was ~10% in each group. Half of the cigarette abstainers in the e-cigarette group were using e-cigarettes at W3. Different methods to help quitting had statistically comparable 12+ month cigarette abstinence at W3 (e-cigarettes vs no product: Risk Difference (RD) = 0.01, 95% CI: -0.04 to 0.06; e-cigarettes vs pharmacotherapy: RD = 0.02, 95% CI:-0.04 to 0.09). Likewise, daily e-cigarette users at W2 did not show a cessation benefit over comparable no-e-cigarette users and this finding was robust to sensitivity analyses. Abstinence for 30+ days at W3 was also similar across products.<h4>Limitations</h4>The frequency of e-cigarette use during the LQA was not assessed, nor was it possible to assess continuous abstinence from the LQA.<h4>Conclusion</h4>Among US daily smokers who quit cigarettes in 2014-15, use of e-cigarettes in that attempt compared to approved cessation aids or no products showed similar abstinence rates 1-2 years later.https://doi.org/10.1371/journal.pone.0237938 |
spellingShingle | John P Pierce Tarik Benmarhnia Ruifeng Chen Martha White David B Abrams Bridget K Ambrose Carlos Blanco Nicolette Borek Kelvin Choi Blair Coleman Wilson M Compton K Michael Cummings Cristine D Delnevo Tara Elton-Marshall Maciej L Goniewicz Shannon Gravely Geoffrey T Fong Dorothy Hatsukami James Henrie Karin A Kasza Sheila Kealey Heather L Kimmel Jean Limpert Raymond S Niaura Carolina Ramôa Eva Sharma Marushka L Silveira Cassandra A Stanton Michael B Steinberg Ethel Taylor Maansi Bansal-Travers Dennis R Trinidad Lisa D Gardner Andrew Hyland Samir Soneji Karen Messer Role of e-cigarettes and pharmacotherapy during attempts to quit cigarette smoking: The PATH Study 2013-16. PLoS ONE |
title | Role of e-cigarettes and pharmacotherapy during attempts to quit cigarette smoking: The PATH Study 2013-16. |
title_full | Role of e-cigarettes and pharmacotherapy during attempts to quit cigarette smoking: The PATH Study 2013-16. |
title_fullStr | Role of e-cigarettes and pharmacotherapy during attempts to quit cigarette smoking: The PATH Study 2013-16. |
title_full_unstemmed | Role of e-cigarettes and pharmacotherapy during attempts to quit cigarette smoking: The PATH Study 2013-16. |
title_short | Role of e-cigarettes and pharmacotherapy during attempts to quit cigarette smoking: The PATH Study 2013-16. |
title_sort | role of e cigarettes and pharmacotherapy during attempts to quit cigarette smoking the path study 2013 16 |
url | https://doi.org/10.1371/journal.pone.0237938 |
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