In-hospital outcomes in preterm and small-for-gestational-age newborns: a cohort study

ABSTRACT Objective To compare in-hospital outcomes between small-for-gestational-age and appropriate-for-gestational-age preterm neonates who needed intensive care. Methods A retrospective cohort study with preterm newborns, from January to December 2017. The results are presented as median, fre...

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Main Authors: Lo-Ruama Pereira Costa, Gleise Aparecida Moraes Costa, Cristina Ortiz Sobrinho Valete, José Kleber Kobol Machado, Mariliza Henrique da Silva
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2022-05-01
Series:Einstein (São Paulo)
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100251&lng=en&tlng=en
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author Lo-Ruama Pereira Costa
Gleise Aparecida Moraes Costa
Cristina Ortiz Sobrinho Valete
José Kleber Kobol Machado
Mariliza Henrique da Silva
author_facet Lo-Ruama Pereira Costa
Gleise Aparecida Moraes Costa
Cristina Ortiz Sobrinho Valete
José Kleber Kobol Machado
Mariliza Henrique da Silva
author_sort Lo-Ruama Pereira Costa
collection DOAJ
description ABSTRACT Objective To compare in-hospital outcomes between small-for-gestational-age and appropriate-for-gestational-age preterm neonates who needed intensive care. Methods A retrospective cohort study with preterm newborns, from January to December 2017. The results are presented as median, frequency, and odds ratio. Numerical variables were compared using the Wilcoxon test. Categorical variables were compared using the χ2 test. We considered p<0.05 as significant. Results Out of 129 preterm newborns included, 20.9% were small-for-gestational-age. Median gestational age was 31 2/7 weeks, birthweight was 1,450g, and length of hospital stay was 39 days. Preterm small-for-gestational-age newborns presented a higher chance of peri-intraventricular hemorrhage (odds ratio of 3.23; p=0.02), retinopathy of prematurity (odds ratio of 2.78 p=0.02), patent ductus arteriosus (odds ratio of 2.50; p=0.04) and a lower chance of presumptive early-onset sepsis (odds ratio of 0.37; p=0.03). Conclusion Preterm small-for-gestational-age neonates were associated with peri-intraventricular hemorrhage, retinopathy of prematurity and patent ductus arteriosus. This emphasizes the need of special care for these neonates.
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spelling doaj.art-96bf3360eb6842a6b10b5141487d0cd02022-12-22T02:09:44ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)2317-63852022-05-012010.31744/einstein_journal/2022ao6781In-hospital outcomes in preterm and small-for-gestational-age newborns: a cohort studyLo-Ruama Pereira Costahttps://orcid.org/0000-0003-0832-0060Gleise Aparecida Moraes Costahttps://orcid.org/0000-0001-9972-5607Cristina Ortiz Sobrinho Valetehttps://orcid.org/0000-0002-6925-4346José Kleber Kobol Machadohttps://orcid.org/0000-0002-8151-7233Mariliza Henrique da Silvahttps://orcid.org/0000-0003-2194-8805ABSTRACT Objective To compare in-hospital outcomes between small-for-gestational-age and appropriate-for-gestational-age preterm neonates who needed intensive care. Methods A retrospective cohort study with preterm newborns, from January to December 2017. The results are presented as median, frequency, and odds ratio. Numerical variables were compared using the Wilcoxon test. Categorical variables were compared using the χ2 test. We considered p<0.05 as significant. Results Out of 129 preterm newborns included, 20.9% were small-for-gestational-age. Median gestational age was 31 2/7 weeks, birthweight was 1,450g, and length of hospital stay was 39 days. Preterm small-for-gestational-age newborns presented a higher chance of peri-intraventricular hemorrhage (odds ratio of 3.23; p=0.02), retinopathy of prematurity (odds ratio of 2.78 p=0.02), patent ductus arteriosus (odds ratio of 2.50; p=0.04) and a lower chance of presumptive early-onset sepsis (odds ratio of 0.37; p=0.03). Conclusion Preterm small-for-gestational-age neonates were associated with peri-intraventricular hemorrhage, retinopathy of prematurity and patent ductus arteriosus. This emphasizes the need of special care for these neonates.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100251&lng=en&tlng=enInfant, prematureInfant newbornInfant, small for gestational ageRetinopathy of prematurityEnterocolitis, necrotizingInfant, premature, diseasesCritical care
spellingShingle Lo-Ruama Pereira Costa
Gleise Aparecida Moraes Costa
Cristina Ortiz Sobrinho Valete
José Kleber Kobol Machado
Mariliza Henrique da Silva
In-hospital outcomes in preterm and small-for-gestational-age newborns: a cohort study
Einstein (São Paulo)
Infant, premature
Infant newborn
Infant, small for gestational age
Retinopathy of prematurity
Enterocolitis, necrotizing
Infant, premature, diseases
Critical care
title In-hospital outcomes in preterm and small-for-gestational-age newborns: a cohort study
title_full In-hospital outcomes in preterm and small-for-gestational-age newborns: a cohort study
title_fullStr In-hospital outcomes in preterm and small-for-gestational-age newborns: a cohort study
title_full_unstemmed In-hospital outcomes in preterm and small-for-gestational-age newborns: a cohort study
title_short In-hospital outcomes in preterm and small-for-gestational-age newborns: a cohort study
title_sort in hospital outcomes in preterm and small for gestational age newborns a cohort study
topic Infant, premature
Infant newborn
Infant, small for gestational age
Retinopathy of prematurity
Enterocolitis, necrotizing
Infant, premature, diseases
Critical care
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082022000100251&lng=en&tlng=en
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